生物材料表面改性以及具有特定结构与功能的先进生物材料的合成始终是生物材料研究的核心课题.原子转移自由基聚合( ATRP)是一种新型自由基聚合,在生物材料表面改性以及新型生物材料合成方面具有巨大的应用前景.利用ATRP技术可以提高生物材料表面生物相容性、生物适应性以及生物功能性,如提高材料表面的抗生物污染性、血液相容性、细胞相容性以及抗菌性能等；同时,ATRP也可用于合成新型生物医用高分子材料,如两亲性高分子、纳米胶束、智能水凝胶以及一些具有特殊结构的高分子(包括星型、超支化、梳型高分子等).ATRP技术与点击化学结合,可形成新的生物活性表面或者合成新的生物材料,可望产生更多的功能化的材料表面与生物材料.
参考文献
| [1] | Edmondson, S.;Nguyen, N.T.;Lewis, A.L.;Armes, S.P. .Co-nonsolvency effects for surface-initiated poly(2-(methacryloyloxy)ethyl phosphorylcholine) brushes in alcohol/water mixtures[J].Langmuir: The ACS Journal of Surfaces and Colloids,2010(10):7216-7226. |
| [2] | Zhang Z;Chen S F;Chang Y et al.Surface grafted sulfobetaine polymers via atom transfer radical polymerization as supcrlow fouling coatings[J].Journal of Physical Chemistry B,2006,110:10799. |
| [3] | Pizarro G D;Marambio O G;Jeria-Orell M et al.Amphiphilic diblock copolymers poly(2-hydroxyethylmethacrylate)-b-(N-phenylmaleimide) and poly(2-hydroethylmethacrylatc)-b-(styrene) using the macroinitiator poly(HEMA)Cl by ATRP:Preparation,characterization,and thermal properties[J].Journal of Applied Polymer Science,2010,118(06):3649. |
| [4] | Zeng, L.;Wang, H.;Fu, G.;Jiang, J.;Zhang, X. .A new approach for synthesis of the comb-shaped poly (ε-caprolactone) brushes on the surface of nano-hydroxyapatite by combination of ATRP and ROP[J].Journal of Colloid and Interface Science,2010(1):36-42. |
| [5] | Wei QS;Ji J;Shen JC .Synthesis of near-infrared responsive gold nanorod/PNIPAAm core/shell nanohybrids via surface initiated ATRP for smart drug delivery[J].Macromolecular rapid communications: Publishing the newsletters of the European Polymer Federation,2008(8):645-650. |
| [6] | Yuan Ping;Cheng-De Liu;Gu-Ping Tang;Jian-Shu Li;Jun Li;Wan-Tai Yang;Fu-Jian Xu .Functionalization of Chitosan via Atom Transfer Radical Polymerization for Gene Delivery[J].Advanced functional materials,2010(18):3106-3116. |
| [7] | Craig J.Hawker;Anton W.Bosman;Eva Harth .New Polymer Synthesis by Nitroxide Mediated Living Radical Polymerizations[J].Chemical Reviews,2001(12):3661-3688. |
| [8] | Chiefari J.;Ercole F.;Krstina J.;Jeffery J.;Le TPT. Mayadunne RTA.;Meijs GF.;Moad CL.;Moad G.;Rizzardo E.;Thang SH.;Chong YK. .Living free-radical polymerization by reversible addition-fragmentation chain transfer: The RAFT process[J].Macromolecules,1998(16):5559-5562. |
| [9] | Masami Kamigaito;Tsuyoshi Ando;Mitsuo Sawamoto .Metal-Catalyzed Living Radical Polymerization[J].Chemical Reviews,2001(12):3689-3745. |
| [10] | Hester JF.;Banerjee P.;Won YY.;Akthakul A.;Acar MH.;Mayes AM. .ATRP of amphiphilic graft copolymers based on PVDF and their use as membrane additives[J].Macromolecules,2002(20):7652-7661. |
| [11] | Xu F J;Li Y L;Kang E T et al.Heparin-coupled poly(poly(ethylene glycol) monomethacrylate)-Si(111) hybrids and their blood compatible surfaces[J].Biomacromolecules,2005,6:1759. |
| [12] | Bozukova D;Pagnoulle C;De Pauw-Gillet MC;Ruth N;Jerome R;Jerome C .Imparting antifouling properties of poly(2-hydroxyethyl methacrylate) hydrogels by grafting poly(oligoethylene glycol methyl ether acrylate)[J].Langmuir: The ACS Journal of Surfaces and Colloids,2008(13):6649-6658. |
| [13] | Feng W;Brash JL;Zhu SP .Non-biofouling materials prepared by atom transfer radical polymerization grafting of 2-methacryloloxyethyl phosphorylcholine: Separate effects of graft density and chain length on protein repulsion[J].Biomaterials,2006(6):847-855. |
| [14] | Campoccia D;Montanaro L;Arciola CR .The significance of infection related to orthopedic devices and issues of antibiotic resistance.[J].Biomaterials,2006(11):2331-2339. |
| [15] | Piper C;K(o)rfer R;Horstkotte D .Valve disease:Prosthetic valve endocarditis[J].Heart,2001,85:590. |
| [16] | Vongpatanasin W;Hillis D;Lange R A .Medical progress:Prosthetic heart valves[J].New England Journal of Medicine,1996,335:407. |
| [17] | Yao F;Fu G D;Zhao J P et al.Antibacterial effect of surface-functionalized polypropylene hollow fiber membrane from surface-initiated atom transfer radical polymerization[J].Journal of Membrane Science,2008,319:149. |
| [18] | Cheng G;Zhang Z;Chen S;Bryers JD;Jiang S .Inhibition of bacterial adhesion and biofilm formation on zwitterionic surfaces.[J].Biomaterials,2007(29):4192-4199. |
| [19] | Yang, W;Xue, H;Li, W;Zhang, JL;Jiang, SY .Pursuing "Zero" Protein Adsorption of Poly(carboxybetaine) from Undiluted Blood Serum and Plasma[J].Langmuir: The ACS Journal of Surfaces and Colloids,2009(19):11911-11916. |
| [20] | Shen M C;Pan Y V;Wagner M S et al.Inhibition of monocyte adhesion and fibrinogen adsorption on glow discharge plasma deposited tetraethylene glycol dimethyl ether[J].Journal of Biomaterials Science:Polymer Edition,2001,12:961. |
| [21] | Yang W;Chen SF;Cheng G;Vaisocherova H;Xue H;Li W;Zhang JL;Jiang SY .Film thickness dependence of protein adsorption from blood serum and plasma onto poly(sulfobetaine)-grafted surfaces[J].Langmuir: The ACS Journal of Surfaces and Colloids,2008(17):9211-9214. |
| [22] | Zhang Z;Chen S;Jiang S .Dual-functional biomimetic materials:Nonfouling poly(carboxybetaine) with active functional groups for protein immobilization[J].Biomacromolecules,2006,7:3311. |
| [23] | Liu P S;Chen Q;Liu X et al.Grafting of zwitterion from cellulose membranes via ATRP for improving blood compatibility[J].Biomacromolecules,2009,10:2809. |
| [24] | Lavanant, L;Pullin, B;Hubbell, JA;Klok, HA .A Facile Strategy for the Modification of Polyethylene Substrates with Non-Fouling, Bioactive Poly(poly(ethylene glycol) methacrylate) Brushes[J].Macromolecular bioscience,2010(1):101-108. |
| [25] | Tugulu S;Silacci P;Stergiopulos N;Klok HA .RGD - Functionalized polymer brushes as substrates for the integrin specific adhesion of human umbilical vein endothelial cells[J].Biomaterials,2007(16):2536-2546. |
| [26] | Wei J C;He P;Liu A X et al.Surface modification of hydroxyapatite nanoparticles with thermal-responsive PNIPAM by ATRP[J].Macromolecular Bioscience,2009,9:1237. |
| [27] | Shuhui Qin;Dongqi Qin;Warren T. Ford;Daniel E. Resasco;Jose E. Herrera .Polymer Brushes on Single-Walled Carbon Nanotubes by Atom Transfer Radical Polymerization of n-Butyl Methacrylate[J].Journal of the American Chemical Society,2004(1):170-176. |
| [28] | Fan QL;Neoh KG;Kang ET;Shuter B;Wang SC .Solvent-free atom transfer radical polymerization for the preparation of poly(poly(ethyleneglycol) monomethacrylate)-grafted Fe(3)O(4) nanoparticles: Synthesis, characterization and cellular uptake.[J].Biomaterials,2007(36):5426-5436. |
| [29] | Xu FJ;Kang ET;Neoh KG .pH- and temperature-responsive hydrogels from crosslinked triblock copolymers prepared via consecutive atom transfer radical polymerizations[J].Biomaterials,2006(14):2787-2797. |
| [30] | Kibret Mequanint;Alpesh Patel;Deon Bezuidenhout .Synthesis,Swelling Behavior,and Biocompatibility of Novel Physically Cross-Linked Polyurethane-block-Poly(glycerol methacrylate) Hydrogels[J].Biomacromolecules,2006(3):883-891. |
| [31] | Newland, B.;Tai, H.;Zheng, Y.;Velasco, D.;Di Luca, A.;Howdle, S.M.;Alexander, C.;Wang, W.;Pandit, A. .A highly effective gene delivery vector - Hyperbranched poly(2-(dimethylamino)ethyl methacrylate) from in situ deactivation enhanced ATRP[J].Chemical communications,2010(26):4698-4700. |
| [32] | Xu F J;Ping Y;Ma J et al.Comb-shaped copolymers composed of hydroxypropyl cellulose backbones and cationic poly ((2-dimethyl amino)ethyl methacrylate) side chains for gene delivery[J].Bioconjugate Chemistry,2009,20:1449. |
| [33] | Koh, JK;Kim, YW;Ahn, SH;Min, BR;Kim, JH .Antifouling Poly(vinylidene fluoride) Ultrafiltration Membranes Containing Amphiphilic Comb Polymer Additive[J].Journal of Polymer Science, Part B. Polymer Physics,2010(2):183-189. |
| [34] | Bencherif S A;Gao H F;Srinivasan A et al.Cell-adhesive star polymers prepared by ATRP[J].Biomacromolecules,2009,10:1795. |
| [35] | Wang XS;Guerin G;Wang H;Wang YS;Manners I;Winnik MA .Cylindrical block copolymer micelles and co-micelles of controlled length and architecture[J].Science,2007(5838):644-647. |
| [36] | Yu, SY;Azzam, T;Rouiller, I;Eisenberg, A ."Breathing" Vesicles[J].Journal of the American Chemical Society,2009(30):10557-10566. |
| [37] | Elizabeth S. Read;Steven P. Armes .Recent advances in shell cross-linked micelles[J].Chemical communications,2007(29):3021-3035. |
| [38] | Zhang Q.;Wooley KL.;Remsen EE. .Shell cross-linked nanoparticles containing hydrolytically degradable, crystalline core domains[J].Journal of the American Chemical Society,2000(15):3642-3651. |
| [39] | Sugihara S;Armes S P;Lewis A L .One-pot synthesis of biomimetic shell cross-linked micelles and nanocages by ATRP in alcohol/water mixtures[J].Angewandte Chemie International Edition,2010,49:3500. |
| [40] | Tan B H;Hussain H;Liu Y et al.Synthesis and self-assembly of brush-type poly[poly (ethylene glycol) methyl ether methacrylate]-block-poly(pentafluorostyrene) amphophilic diblock copolymers in aqueous solution[J].Langmuir,2010,26(04):2361. |
| [41] | Lutz JF;Borner HG;Weichenhan K .Combining ATRP and "click" chemistry: a promising platform toward functional biocompatible polymers and polymer bioconjugates[J].Macromolecules,2006(19):6376-6383. |
| [42] | Golas P L;Matyjaszewski K .Click chemistry and ATRP:A beneficial union for the preparation of functional materials[J].QSAR and Combinatorial Science,2007,26(11-12):1116. |
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