采用一种简单的方法制备偏磷酸钙生物陶瓷晶须材料以达到增强聚左旋乳酸的目的.即将熔融所得CaO-P2O5玻璃在非晶相-晶相转变温度热处理一段时间后用40℃的0.1mol/L NaOH溶液洗滤,生成直径为1～5μm,长径比达30～50的晶须.探讨了原料钙磷比、热处理时间、洗滤时间和晶核剂对晶须形貌的影响.在钙磷比为0.85,热处理时间和洗滤时间分别为36h和48h的实验条件下可以得到主晶相为β-偏磷酸钙(β-CMP)的陶瓷晶须.加入25wt%的β-CMPw后β-偏磷酸钙/聚左旋乳酸(β-CMPw/PLLA)复合材料的弯曲模量达4.3GPa,较纯PLLA提高了约14.4%.
参考文献
| [1] | 任杰,周新宇.羟基磷灰石/聚乳酸及其共聚物复合生物材料[J].上海生物医学工程,2004(01):46-50,41. |
| [2] | 邹俊,李新松,哈涌泉,韩凤俊.超细β-磷酸三钙/聚-L-乳酸复合材料的制备与骨折内固定器的加工[J].东南大学学报(医学版),2004(03):155-159. |
| [3] | Youngmee Jung;Soo Hyun Kim;Sang-Soo Kim;Hee Jin You;Byoung-Soo Kim;Sukyoung Kim;Sang-Heon Kim;Young Ha Kim .Tissue Engineered Bone Formation with Polymer/ Ceramic Composites by Press-And-Baking Method[J].Key engineering materials,2005(288/289):79-82. |
| [4] | Dias AG.;Lopes MA.;Gibson IR.;Santos JD. .In vitro degradation studies of calcium phosphate glass ceramics prepared by controlled crystallization[J].Journal of Non-Crystalline Solids: A Journal Devoted to Oxide, Halide, Chalcogenide and Metallic Glasses, Amorphous Semiconductors, Non-Crystalline Films, Glass-Ceramics and Glassy Composites,2003(1/3):81-89. |
| [5] | 张喆壁 .偏磷酸钙生物活性玻璃陶瓷纤维的研究[J].山东建材学院学报,1995,9(01):52. |
| [6] | Victoria Guencheva et al.Induced crystallization of glassforming melts.Part 1.Heterogeneous nucleation effect of noble metal microcrystals on the crystallization of calcium metaphosphate[J].Glass Sci Techn,2004,77(05):217. |
| [7] | Youngmee Jung;Sang-Soo Kim;YoungHa Kim et al.A poly(lactic acid)/calcium metaphosphate composite for bone tissue engineering[J].Biomaterials,2005,26:6314. |
| [8] | Toshihiro Kasuga;Yoshio Ota;Masayuki Nogami et al.Surface modification of calcium metaphosphate fibers[J].Journal of Materials Science:Materials in Medicine,2000,11:223. |
| [9] | Eui Kyun Parka et al.Cellular biocompatibility and stimulatory effects of calcium metaphosphate on osteoblastic differentiation of human bone marrow-derived stromal cells[J].BIOMATERIALS,2004,25:348. |
| [10] | 张淑霞,李建保,李惟,黄勇.用玻璃结晶化方法制备的偏磷酸钙晶须及其形貌[J].硅酸盐学报,1999(05):569-574. |
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