本文采用有限体积法数值模拟了轴向方波电场和直流电场作用下,具有不同电泳淌度粒子的运动情况.结果表明,在半个方波电场周期内,具有不同电泳淌度的粒子在相同的时间内达到各自的稳定速度,周期变化的方波电场使微粒子在微通道内做往复的运动;在直流电场作用下,两个不同电泳淌度的粒子会在轴向方向上产生位移差.定义从溶液中分离粒子的最短距离与微通道高度的比值为分离效率,数值模拟结果表明,分离效率随横向电场强度和粒子电泳淌度的增加而减小.
参考文献
| [1] | Gascoyne PRC.;Vykoukal J. .Particle separation by dielectrophoresis [Review][J].Electrophoresis: The Official Journal of the International Electrophoresis Society,2002(13):1973-1983. |
| [2] | Cummings EB.;Singh AK. .Dielectrophoresis in microchips containing arrays of insulating posts: Theoretical and experimental results[J].Analytical chemistry,2003(18):4724-4731. |
| [3] | Lapizco-Eneinas B H;Simmons B A;Cummings E B et al.Dielectrophoretic Concentration and Separation of Live and Dead Bacteria in an Array of Insulators[J].Analytical Chemistry,2004,76:571-1579. |
| [4] | Chou CF;Tegenfeldt JO;Bakajin O;Chan SS;Cox EC;Darnton N;Duke T;Austin RH .Electrodeless dielectrophoresis of single- and double-stranded DNA.[J].Biophysical Journal,2002(4):2170-2179. |
| [5] | Ying L;White S S .Frequency and Voltage Dependence of the Dielectrophoretic Trapping of Short Lengths of DNA and dCTP in a Nanopipette[J].Biophysical Journal,2004,86:1018-1027. |
| [6] | Kang KH;Kang Y;Xuan X;Li D .Continuous separation of microparticles by size with direct current-dielectrophoresis.[J].Electrophoresis: The Official Journal of the International Electrophoresis Society,2006(3):694-702. |
| [7] | Jones T B.Electromechanics of Particles[M].Cambridge:Cambridge University Press,1995 |
| [8] | Morgan H;Green N G.AC Electrokinetics:Colloids and Nanoparticles[M].Research Studies Press,Baldock,Hertfordshire,England,2002 |
| [9] | Chein R;Yang YC;Lin Y .Estimation of Joule heating effect on temperature and pressure distribution in electrokinetic-driven microchannel flows.[J].Electrophoresis: The Official Journal of the International Electrophoresis Society,2006(3):640-649. |
| [10] | Patankar N A;Hu H H .Numerical Simulation of Electroosmotic Flow[J].Analytical Chemistry,1998,70:870-1881. |
| [11] | Burgreen D;Nakache F .Electrokinetic Flow in Ultrafine Capillary Slits[J].Journal of Physical Chemistry,1964,68:084-1091. |
| [12] | Harrison D J;Fluri K;Seller K et al.Micromachining a Miniaturized Capillary Electrophoresis-Based Chemical Analysis System on a Chip[J].Science,1993,261:95-897. |
| [13] | Zhi C;Anuj C H .DNA Separation by EFFF in a Microchannel[J].Journal of Colloid and Interface Science,2005,285:34-844. |
| [14] | Sia SK;Whitesides GM .Microfluidic devices fabricated in Poly(dimethylsiloxane) for biological studies.[J].Electrophoresis: The Official Journal of the International Electrophoresis Society,2003(21):3563-3576. |
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