本文对北京市167对匹配母亲静脉血与脐带血中15种全氟化合物前体物质浓度水平与胎盘透过率进行了分析．研究结果表明，6∶2氟调聚磺酸（6∶2 FTS），N?甲基全氟辛基磺酰胺乙酸（NMeFOSAA）在母亲静脉血与脐带血中均以较高检出率检出（81％与74％，母亲静脉血；90％与67％，脐带血），浓度范围分别为＜LOD （3．00）—203．00 pg·mL－1与＜LOD （0．30）—46．79 pg·mL－1（母亲静脉血），＜LOD （3．00）—252．12 pg·mL－1与＜LOD （0．30）—16．00 pg·mL－1（脐带血）；全氟辛基磺酰胺（ FOSA ）， N?乙基全氟辛基磺酰胺乙酸（NEtFOSAA）则在匹配血样中检出率和浓度水平较低；8∶2 FTS，N?乙基全氟辛基磺酰胺（NEtFOSA）仅在母亲静脉血中以较低检出率检出．6∶2 FTS与NMeFOSAA的母血浓度与脐带血浓度呈正相关关系，6∶2 FTS胎盘透过率高于NMeFOSAA．本研究提示了全氟化合物前体物质在人体内的胎盘转移和产前暴露情况．
Perfluoroalkyl acids ( PFASs) precursors, as the indirect source of PFAS contamination, have been observed in environmental and human samples worldwide. In this study, 167 paired maternal and cord serum samples collected in Beijing city were analyzed for fifteen different PFAS precursors. 6∶2 fluorotelomer sulfonate (6∶2 FTS) and N?methyl perfluorooctanesulfonamidoacetates ( NMeFOSAA) had high detection frequencies in both maternal and cord sera ( 81% and 74%, maternal sera;90% and 67%, cord sera) , while the mean concentrations and detection frequencies of perfluorooctane sulfonamide ( FOSA ) and N?ethyl perfluorooctanesulfonamidoacetates ( NEtFOSAA) were lower in paired sera. The concentration ranges of 6∶2 FTS and NMeFOSAA in maternal sera were
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