药品和个人护理用品（ Pharmaceuticals and personal care products， PPCPs）在环境中广泛存在，威胁生态环境和人类健康，受到越来越多的关注。本文综述了固体基底中PPCPs的检测方法，总结了国内外污泥、土壤、沉积物等基底中PPCPs的污染现状，并对PPCPs的进一步研究进行了展望。结果表明，PPCPs的检测方法朝多样化和趋优化的方向发展。污泥样品中PPCPs种类多、浓度高（μg·kg－1—mg·kg－1），土壤和沉积物中虽然浓度不高，但是总量不可小觑。目前，固体基底中的PPCPs还需要更全面和更广泛的研究。
Pharmaceuticals and personal care products ( PPCPs ) are a class of emerging contaminants widely existing in environment. Great concerns have been raised about PPCPs due to the potential adverse impacts on the ecological environment and human health. This paper summarized the analytical methods for the PPCPs detection in the solid matrix. In addition, the current contamination status of PPCPs in sewage sludges, soils and sediments were reviewed. The results demonstrated that the analytical methods of PPCPs were becoming diversified and effective. Many PPCPs were detected in the μg·kg-1—mg·kg-1 level in the sludge, soil and sediment, depending on the species of PPCPs and samples. Based on this review, PPCPs in solid matrix need comprehensive and wide investigation.
参考文献
| [1] | Daughton C G,Ternes T A .Pharmaceuticals and personal care products in the environment:Agents of subtle change?[J].Environ Health Persp,1999,107(6):907-938. |
| [2] | Sun Q,Lv M,Hu A,et al.Seasonal variation in the occurrence and removal of pharmaceuticals and personal care products in a wastewater treatment plant in Xiamen,China [J].J Hazard Mater,doi.org/10.1016/j.jhazmat.2013.11.056. |
| [3] | Reinthaler F F,Posch J,Feierl G,et al .Antibiotic resistance of E-coli in sewage and sludge[J].Water Res,2003,37(8):1685-1690. |
| [4] | van Aerle R,Nolan M,Jobling S,et al .Sexual disruption in a second species of wild cyprinid fish (the gudgeon,Gobio gobio) in United Kingdom freshwaters[J].Environ Toxicol Chem,2001,20(12):2841-2847. |
| [5] | 乔铁军,张锡辉,欧慧婷.药品和个人护理用品在水环境中污染状况的研究与展望[J].给水排水,2009(07):121-130. |
| [6] | 刘莹,管运涛,水野忠雄,张锡辉,津野洋,祝万鹏,黄霞.药品和个人护理用品类污染物研究进展[J].清华大学学报（自然科学版）,2009(03):368-372. |
| [7] | 贾瑷,胡建英,孙建仙,施嘉琛.环境中的医药品与个人护理品[J].化学进展,2009(02):389-399. |
| [8] | 代朝猛,周雪飞,张亚雷,段艳平.环境介质中药物和个人护理品的潜在风险研究进展[J].环境污染与防治,2009(02):77-80. |
| [9] | Bu Q W,Wang B,Huang J,et al .Pharmaceuticals and personal care products in the aquatic environment in China:A review[J].J Hazard Mater,2013,262 |
| [10] | Stevens J L,Northcott G L,Stern G A,et al .PAHs,PCBs,PCNs,organochlorine pesticides,synthetic musks,and polychlorinated n-alkanes in UK sewage sludge:Survey results and implications[J].Environ Sci Technol,2003,37(3):462-467. |
| [11] | Pryor S W,Hay A G,Walker L P .Nonylphenol in anaerobically digested sewage sludge from New York state[J].Environ Sci Technol,2002,36(17):3678-3682. |
| [12] | Yu Y,Wu L S .Analysis of endocrine disrupting compounds,pharmaceuticals and personal care products in sewage sludge by gas chromatography-mass spectrometry[J].Talanta,2012,89 |
| [13] | Xu J,Wu L,Chen W,et al .Simultaneous determination of pharmaceuticals,endocrine disrupting compounds and hormone in soils by gas chromatography-mass spectrometry[J].J Chromatogr A,2008,1202(2):189-195. |
| [14] | Salgado R,Noronha J P,Oehmen A,et al .Analysis of 65 pharmaceuticals and personal care products in 5 wastewater treatment plants in Portugal using a simplified analytical methodology[J].Water Sci Technol,2010,62(12):2862-2871. |
| [15] | Okuda T,Yamashita N,Tanaka H,et al .Development of extraction method of pharmaceuticals and their occurrences found in Japanese wastewater treatment plants[J].Environ Int,2009,35(5):815-820. |
| [16] | Yu Y Y,Huang Q X,Cui J L,et al .Determination of pharmaceuticals,steroid hormones,and endocrine-disrupting personal care products in sewage sludge by ultra-high-performance liquid chromatography-tandem mass spectrometry[J].Anal Bioanal Chem,2011,399(2):891-902. |
| [17] | Chen F,Ying G G,Yang J F,et al .Rapid resolution liquid chromatography-tandem mass spectrometry method for the determination of endocrine disrupting chemicals (EDCs),pharmaceuticals and personal care products (PPCPs) in wastewater irrigated soils[J].J Environ Sci Heal B,2010,45(7):682-693. |
| [18] | Mottaleb M A,Usenko S,O′Donnell J G,et al .Gas chromatography-mass spectrometry screening methods for select UV filters,synthetic musks,alkylphenols,an antimicrobial agent,and an insect repellent in fish[J].J Chromatogr A,2009,1216(5):815-823. |
| [19] | Zuloaga O,Navarro P,Bizkarguenaga E,et al .Overview of extraction,clean-up and detection techniques for the determination of organic pollutants in sewage sludge:A review[J].Anal Chim Acta,2012,736 |
| [20] | Gobel A,Thomsen A,McArdell C S,et al .Extraction and determination of sulfonamides,macrolides,and trimethoprim in sewage sludge[J].J Chromatogr A,2005,1085(2):179-189. |
| [21] | Ramos L .Critical overview of selected contemporary sample preparation techniques[J].J Chromatogr A,2012,1221 |
| [22] | Golet E M,Strehler A,Alder A C,et al .Determination of fluoroquinolone antibacterial agents in sewage sludge and sludge-treated soil using accelerated solvent extraction followed by solid-phase extraction[J].Anal Chem,2002,74(21):5455-5462. |
| [23] | Difrancesco A M,Chiu P C,Standley L J,et al .Dissipation of fragrance materials in sludge-amended soils[J].Environ Sci Technol,2004,38(1):194-201. |
| [24] | Petrovic M,Barcelo D,Diaz A,et al .Low nanogram per liter determination of halogenated nonylphenols,nonylphenol carboxylates,and their non-halogenated precursors in water and sludge by liquid chromatography electrospray tandem mass spectrometry[J].J Am Soc Mass Spectr,2003,14(5):516-527. |
| [25] | Wu C X,Spongberg A L,Witter J D,et al .Detection of pharmaceuticals and personal care products in agricultural soils receiving biosolids application[J].Clean-Soil Air Water,2010,38(3):230-237. |
| [26] | Kinney C A,Furlong E T,Zaugg S D,et al .Survey of organic wastewater contaminants in biosolids destined for land application[J].Environ Sci Technol,2006,40(23):7207-7215. |
| [27] | Rice S L,Mitra S .Microwave-assisted solvent extraction of solid matrices and subsequent detection of pharmaceuticals and personal care products (PPCPs) using gas chromatography-mass spectrometry[J].Anal Chim Acta,2007,589(1):125-132. |
| [28] | Morales S,Canosa P,Rodriguez I,et al .Microwave assisted extraction followed by gas chromatography with tandem mass spectrometry for the determination of triclosan and two related chlorophenols in sludge and sediments[J].J Chromatogr A,2005,1082(2):128-135. |
| [29] | Barker S A .Matrix solid phase dispersion (MSPD)[J].J Biochem Bioph Methods,2007,70(2):151-162. |
| [30] | Mutavdžic′Pavlovic′ D,Pinušic′ T,Periša M,et al .Optimization of matrix solid-phase dispersion for liquid chromatography tandem mass spectrometry analysis of 12 pharmaceuticals in sediments[J].J Chromatogr A,2012,1258 |
| [31] | Lee H B,Peart T E,Sarafin K .Occurrence of polycyclic and nitro musk compounds in Canadian sludge and wastewater samples[J].Water Qual Res J Can,2003,38(4):683-702. |
| [32] | Sagrista E,Larsson E,Ezoddin M,et al .Determination of non-steroidal anti-inflammatory drugs in sewage sludge by direct hollow fiber supported liquid membrane extraction and liquid chromatography-mass spectrometry[J].J Chromatogr A,2010,1217(40):6153-6158. |
| [33] | Berset J D,Bigler P,Herren D .Analysis of nitro musk compounds and their amino metabolites in liquid sewage sludges using NMR and mass spectrometry[J].Anal Chem,2000,72(9):2124-2131. |
| [34] | Kupper T,Berset J D,Etter-Holzer R,et al .Concentration and specific loads of polycyclic musks in sewage sludge originating from a monitoring network in Switzerland[J].Chemosphere,2004,54(8):1111-1120. |
| [35] | Osemwengie L I .Determination of synthetic musk compounds in sewage biosolids by gas chromatography/mass spectrometry[J].J Environ Monit,2006,8(9):897-903. |
| [36] | Jelic A,Petrovic M,Barcelo D .Multi-residue method for trace level determination of pharmaceuticals in solid samples using pressurized liquid extraction followed by liquid chromatography/quadrupole-linear ion trap mass spectrometry[J].Talanta,2009,80(1):363-371. |
| [37] | La Guardia M J,Hale R C,Harvey E,et al .Alkylphenol ethoxylate degradation products in land-applied sewage sludge (biosolids)[J].Environ Sci Technol,2001,35(24):4798-4804. |
| [38] | Davis E F,Klosterhaus S L,Stapleton H M .Measurement of flame retardants and triclosan in municipal sewage sludge and biosolids[J].Environ Int,2012,40 |
| [39] | Xia K,Hundal L S,Kumar K,et al .Triclocarban,triclosan,polybrominated diphenyl ethers,and 4-nonylphenol in biosolids and in soil receiving 33-year biosolids application[J].Environ Toxicol Chem,2010,29(3):597-605. |
| [40] | Chu S G,Metcalfe C D .Simultaneous determination of triclocarban and triclosan in municipal biosolids by liquid chromatography tandem mass spectrometry[J].J Chromatogr A,2007,1164:212-218. |
| [41] | Gonzalez-Marino I,Rodriguez I,Quintana J B,et al .Matrix solid-phase dispersion followed by gas chromatography-mass spectrometry for the determination of triclosan and methyl triclosan in sludge and sediments[J].Anal Bioanal Chem,2010,398(5):2289-2297. |
| [42] | Chen Y S,Yu G,Cao Q M,et al .Occurrence and environmental implications of pharmaceuticals in Chinese municipal sewage sludge[J].Chemosphere,2013,93(9):1765-1772. |
| [43] | Li W H,Shi Y L,Gao L H,et al .Occurrence and removal of antibiotics in a municipal wastewater reclamation plant in Beijing,China[J].Chemosphere,2013,92(4):435-444. |
| [44] | Li W H,Shi Y L,Gao L H,et al .Occurrence,distribution and potential affecting factors of antibiotics in sewage sludge of wastewater treatment plants in China[J].Sci Total Environ,2013,445 |
| [45] | Zeng X Y,Cao S X,Zhang D L,et al .Levels and distribution of synthetic musks and polycyclic aromatic hydrocarbons in sludge collected from Guangdong Province[J].J Environ Sci Heal A,2012,47(3):389-397. |
| [46] | Hu Z J,Shi Y L,Zhang S X,et al .Assessment of synthetic musk fragrances in seven wastewater treatment plants of Beijing,China[J].B Environ Contam Tox,2011,86(3):302-306. |
| [47] | 田艺心,王美娥,陈卫平,汪自强.污水和污泥中的人工合成麝香分析方法[J].生态学杂志,2011(02):395-400. |
| [48] | Sang W,Zhang Y,Zhou X,et al .Spatial and seasonal distribution of synthetic musks in sewage treatment plants of Shanghai,China[J].Water Sci Technol,2012,66(1):201. |
| [49] | 周雪飞,陈家斌,周世兵,张亚雷,石璐.三氯生检测方法的建立与优化[J].中国给水排水,2010(12):126-129. |
| [50] | Chen Z F,Ying G G,Lai H J,et al .Determination of biocides in different environmental matrices by use of ultra-high-performance liquid chromatography-tandem mass spectrometry[J].Anal Bioanal Chem,2012,404(10):3175-3188. |
| [51] | Ye X,Guo X S,Cui X,et al .Occurrence and removal of endocrine-disrupting chemicals in wastewater treatment plants in the Three Gorges Reservoir area,Chongqing,China[J].J Environ Monit,2012,14(8):2204-2211. |
| [52] | 侯绍刚,孙红文.NPnEO在中国北方四城市污水处理厂的污染研究[J].环境科学研究,2006(03):61-66. |
| [53] | Ying G G,Yu X Y,Kookana R S .Biological degradation of triclocarban and triclosan in a soil under aerobic and anaerobic conditions and comparison with environmental fate modelling[J].Environ Pollut,2007,150(3):300-305. |
| [54] | Walters E,McClellan K,Halden R U .Occurrence and loss over three years of 72 pharmaceuticals and personal care products from biosolids-soil mixtures in outdoor mesocosms[J].Water Res,2010,44(20):6011-6020. |
| [55] | Chen Z F,Ying G G,Ma Y B,et al .Occurrence and dissipation of three azole biocides climbazole,clotrimazole and miconazole in biosolid-amended soils[J].Sci Total Environ,2013,452 |
| [56] | Chen Y S S,Yu S,Hong Y W W,et al .Pharmaceutical residues in tidal surface sediments of three rivers in southeastern China at detectable and measurable levels[J].Environ Sci Pollut Res,2013,20(12):8391-8403. |
| [57] | Long E R,Dutch M,Weakland S,et al .Quantification of pharmaceuticals,personal care products,and perfluoroalkyl substances in the marine sediments of Puget Sound,Washington,USA[J].Environ Toxicol Chem,2013,32(8):1701-1710. |
| [58] | Sapozhnikova Y,Liebert D,Wirth E,et al .Polycyclic musk fragrances in sediments and shrimp tissues[J].Polycycl Aromat Comp,2010,30(5):298-308. |
| [59] | Che J S,Yu R P,Song Q J,et al .Determination of synthetic musks in the sediment of the Taihu lake by using accelerated solvent extraction (ASE) and GC/MS[J].Int J Environ an Ch,2011,91(4):387-399. |
| [60] | Sang W J,Zhang Y L,Zhou X F,et al .Occurrence and distribution of synthetic musks in surface sediments of Liangtan River,West China[J].Environ Eng Sci,2012,29(1):19-25. |
| [61] | Zhang X L,Yao Y,Zeng X Y,et al .Synthetic musks in the aquatic environment and personal care products in Shanghai,China[J].Chemosphere,2008,72(10):1553-1558. |
| [62] | Hu Z J,Shi Y L,Cai Y Q .Concentrations,distribution,and bioaccumulation of synthetic musks in the Haihe River of China[J].Chemosphere,2011,84(11):1630-1635. |
| [63] | 冯柳 .松花江水环境中多环麝香的分布特征研究[D].哈尔滨工业大学,2011. |
| [64] | 曾祥英,盛国英,张晓岚,麦碧娴,安太成,傅家谟.城市河流水体沉积物中多环麝香的污染状况[J].环境化学,2008(03):368-370. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%