人工关节是替代病变或损伤关节的植入性假体,除了应满足生物相容性要求外,必须具有足够的耐磨损性能、力学性能和抗氧化性能等.超高分子量聚乙烯因其自身优良的理化性能而被广泛应用于人工关节置换用材料.但随着超高分子量聚乙烯人工植入体使用时间的延长会导致其不同形式的失效,如磨损引起的骨质溶解,给骨科患者生活带来不便.综述了国内外提高超高分子量聚乙烯人工关节植入体综合性能而对材料进行改性处理的各种方法,包括辐照交联、热处理、加入抗氧剂等.最后总结了通过调控流动场诱导形成自增强结构,来改善人工关节植入体力学性能的最新进展,并展望了超高分子量聚乙烯人工关节高性能化的未来研究方向.
参考文献
[1] | Jean Geringer;Witold Tatkiewicz;G. Rouchouse .Wear behavior of PAEK, poly(aryl-ether-ketone), under physiological conditions, outlooks for performing these materials in the field of hip prosthesis[J].Wear: an International Journal on the Science and Technology of Friction, Lubrication and Wear,2011(11/12):2793-2803. |
[2] | Kurtz S M;Ong K L;Schmier J.Future Clinical and Economic Impact of Revision Total Hip and Knee Arthroplasty[A].San Diego:CA,2007:144-151. |
[3] | Kurtz S;Ong K;Lau E;Mowat F;Halpern M .Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030.[J].The Journal of Bone and Joint Surgery. American Volume,2007(4):780-785. |
[4] | Li S;Burstein A H.Ultra-High Molecular Weight Polyethylene.The Material and Its Use in Total Joint Implants[J].Journal of Bone and Joint Surgery-American Volume,1994(76):1080-1090. |
[5] | Muratoglu OK;Bragdon CR;O'Connor DO;Jasty M;Harris WH;Gul R;McGarry F .Unified wear model for highly crosslinked ultra-high molecular weight polyethylenes (UHMWPE).[J].Biomaterials,1999(16):1463-1470. |
[6] | Wittmann J C;Lots B.Polymer Decoration:The Orientation of Polymer Folds as Revealed by The Crystallization of Polymer Vapors[J].Polymer Science Part B:Polymer Physics,1985(23):205-226. |
[7] | Oral E;Rowell SL;Muratoglu OK .The effect of alpha-tocopherol on the oxidation and free radical decay in irradiated UHMWPE[J].Biomaterials,2006(32):5580-5587. |
[8] | Tower SS;Currier JH;Currier BH;Lyford KA;Van-Citters DW;Mayor MB .Rim cracking of the cross-linked longevity polyethylene acetabular liner after total hip arthroplasty.[J].The Journal of Bone and Joint Surgery. American Volume,2007(10):2212-2217. |
[9] | Wang A;Sun D C;Stark C.Wear Mechanisms of UHMWPE in Total Joint Replacement[J].WEAR,1995(181):241-249. |
[10] | Fisher J;Downson D;Hamdzah H.Effect of Sliding Velocity on the Friction and Wear of UHMWPE for Use in Total Artificial Joints[J].WEAR,1994(175):219-255. |
[11] | Xiong DS.;Ge SR. .Friction and wear properties of UHMWPE/Al2O3 ceramic under different lubricating conditions[J].Wear: an International Journal on the Science and Technology of Friction, Lubrication and Wear,2001(1):242-245. |
[12] | Ge S;Huang C.Biotribological Behavior of UHMWPE Hip Joints[A].,2004:68-74. |
[13] | Wang A.;Stark C.;Dumbleton J.H.;Lin R. .Suitability and limitations of carbon fiber reinforced PEEK composites as bearing surfaces for total joint replacements[J].Wear: an International Journal on the Science and Technology of Friction, Lubrication and Wear,1999(2):724-727. |
[14] | Kurtz SM;Muratoglu OK;Evans M;Edidin AA .Advances in the processing, sterilization, and crosslinking of ultra-high molecular weight polyethylene for total joint arthroplasty.[J].Biomaterials,1999(18):1659-1688. |
[15] | McKellop H;Shen FW;Lu B;Campbell P;Salovey R .Development of an extremely wear-resistant ultra high molecular weight polyethylene for total hip replacements.[J].Journal of orthopaedic research,1999(2):157-167. |
[16] | Jasty M;Bragdon C R;O'Connor D O.Marked Improvement in the Wear Resistance of a New Form of UHMWPE in a Physiologic Hip Simulator[A].San Francisco,1997:785. |
[17] | Muratoglu OK;Bragdon CR;O'Connor DO;Jasty M;Harris WH .A novel method of cross-linking ultra-high-molecular-weight polyethylene to improve wear, reduce oxidation, and retain mechanical properties. Recipient of the 1999 HAP Paul Award.[J].The Journal of arthroplasty,2001(2):149-160. |
[18] | Jahan M S;Thomas D E;Trieu H H et al.Investigation of Free Radicals in Shelf-aged Polyethylene Tibial Components[R].Amsterdam:Wright Medical,1996. |
[19] | Jahan M S;King M C;Haggard W O.A Study of Longlived Free Radical sin Gamma-irradiated Medical Grade Polyethylene[J].Radiation Physics and Chemistry,2001(62):141-144. |
[20] | Sohma J;Kawashima T;Shimada S;Kinell P O,B Ranby, Runnstrom-Reio V.ESR Applications to Polymer Research[M].New York:Wiley,1973:225. |
[21] | Scou G.Atmospheric Oxidation and Antioxidants[M].Amsterdam:Elsevier Science Press,1993:45. |
[22] | Wannomae KK;Christensen SD;Freiberg AA;Bhattacharyya S;Harris WH;Muratoglu OK .The effect of real-time aging on the oxidation and wear of highly cross-linked UHMWPE acetabular liners[J].Biomaterials,2006(9):1980-1987. |
[23] | Wannomae KK;Bhattacharyya S;Freiberg A;Estok D;Harris WH;Muratoglu O .In vivo oxidation of retrieved cross-linked ultra-high-molecular-weight polyethylene acetabular components with residual free radicals.[J].The Journal of arthroplasty,2006(7):1005-1011. |
[24] | Currier B;Mayor M;Currier J.Crossfire Retrievals—What Can We Learn[A].Washington:Dartmouth College,2005 |
[25] | Lerf R;Zurbrugg D;Delfosse D .Use of vitamin E to protect cross-linked UHMWPE from oxidation.[J].Biomaterials,2010(13):3643-3648. |
[26] | Gijsman P;Smelt HJ;Schumann D .Hindered amine light stabilizers: An alternative for radiation cross-linked UHMwPE implants.[J].Biomaterials,2010(26):6685-6691. |
[27] | Kurtz SM;Pruitt LA;Jewett CW;Foulds JR;Edidin AA .Radiation and chemical crosslinking promote strain hardening behavior and molecular alignment in ultra high molecular weight polyethylene during multi-axial loading conditions.[J].Biomaterials,1999(16):1449-1462. |
[28] | Gencur SJ;Rimnac CM;Kurtz SM .Failure micromechanisms during uniaxial tensile fracture of conventional and highly crosslinked ultra-high molecular weight polyethylenes used in total joint replacements.[J].Biomaterials,2003(22):3947-3954. |
[29] | Gillis A M;Schmiegg J J;Bhattacharyya S.An Independent Evaluation of the Mechanical,Chemical and Fracture Properties of UHMWPE Crosslinked by 34 Different Conditions[A].Anaheim:CA,1999:908. |
[30] | Gomoll A;Wanich T;Bellare A .J-integral fracture toughness and tearing modulus measurement of radiation cross-linked UHMWPE.[J].Journal of orthopaedic research,2002(6):1152-1156. |
[31] | Greenwald A S;Bauer T W;Ries M D.New Polys for old:Contribution or Caveat[A].San Francisco:The Editorial Committe of this Proceeding,2001 |
[32] | D.A. Baker;R.S. Hastings;L. Pruitt .Study of fatigue resistance of chemical and radiation crosslinked medical grade ultrahigh molecular weight polyethylene[J].Journal of biomedical materials research, Part B. Applied biomaterials,1999(4):573-581. |
[33] | O' Connor D O;Muratoglu O K;Bragdon C R.Wear and High Cycle Fatigue of Highly Crosslinked UHMWPE[A].Anaheim:CA,1999:816. |
[34] | Krzypow D J;Bensusan J;Sevo K.The Fatigue Crack Propagation Resistance of Gamma Radiation or Peroxide Crosslinked UHMW Polyethylene[A].Hawaii:The Editorial Committe of this Proceeding,2000:382. |
[35] | Baker D.A.;Hastings R.S. .Compression and tension fatigue resistance of medical grade ultra high molecular weight polyethylene: the effect of morphology, sterilization, aging and temperature[J].Polymer: The International Journal for the Science and Technology of Polymers,2000(2):795-808. |
[36] | D. A. Baker;A. Bellare;L. Pruitt .The effects of degree of crosslinking on the fatigue crack initiation and propagation resistance of orthopedic-grade polyethylene[J].Journal of biomedical materials research, Part B. Applied biomaterials,2003(1):146-154. |
[37] | Duus L C;Walsh H A;Gillis A M.The Effect of Resin Grade,Manufacturing Method,and Crosslinking on The Fracture Toughness of Commercially Available UHMWPE[J].Transactions of the Orthopeddic Research Society,2000(25):544. |
[38] | 李忠明;黄妍斐;徐家壮 et al.一种人工关节用可熔体加工的超高分子量聚乙烯复合材料[P].China,ZL201310720156.2 |
[39] | Ling Xu;Gan-Ji Zhong;Chen Chen .Tuning the Superstructure of Ultrahigh-Molecular-Weight Polyethylene/Low-Molecular-Weight Polyethylene Blend for Artificial Joint Application[J].ACS applied materials & interfaces,2012(3):1521-1529. |
[40] | 陈晨;徐玲;李忠明 .全关节植入用自增强聚乙烯共混物的制备方法[P].China,ZL201110052173.4,2011-08-31. |
[41] | Yan-Fei Huang;Jia-Zhuang Xu;Jun-Yi Xu .Self-reinforced polyethylene blend for artificial joint application[J].Journal of Materials Chemistry, B. materials for biology and medicine,2014(8):971-980. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分:
-
10%
-
20%
-
30%
-
40%
-
50%