提出一种测量材料表面电荷是非均匀的、没有中性区的弱电荷的方法.即测试时,利用扫描探针显微镜(SPM)的静电力显微镜(EFM)测量技术,依靠轻敲模式(Tapping Mode)和抬举模式(Lift Mode),用相位成像测量有机高分子膜--壳聚糖膜(CHI)的表面电荷密度空间分布,但由于仪器设计中相位的泰勒展开是:sin△φ≈1/2△φ,所以所获的电荷图像只能确定材料的表面电荷分布和表面电荷密度的近似值.然而,嵴宽约为2.12μm表面正电荷微沟槽结构的这种特殊电荷形貌分布有利于细胞的生长,因此获得的表面电荷分布补充了生物材料表面理化性质.
参考文献
| [1] | F Yang;Y Y Yang;X F Zhang et al.Performance modification of Chintosan membranes induced by gamma irradiation[J].Journal of Biomaterials Applications,2002,16:215-25. |
| [2] | 杨吟野,李训虎,李国富,赵南明,张秀芳.壳聚糖和PHBHHx用作神经修复导管材料的研究[J].生物医学工程学杂志,2002(01):25-29. |
| [3] | D Alvarez;J Hartwich;M Fouchier et al.Sub-S nm-spatial resolution in scanning spreading resistance microscopy using fulldiamond tips[J].Applied Physics Letters,2003,82(11):1724-1726. |
| [4] | Roger Proksch;Ken Babcock;Jason Cleveland .Magnetic dissipation microscopy in ambient conditions[J].Applied physics letters,1999(3):419-421. |
| [5] | J P Cleveland;B Anczykowski;A E Schmid et al.Energy dissipation in tapping-mode atomic force microscogy[J].Applied Physics Letters,1998,72(20):2613-2615. |
| [6] | X F Walboomers;H J E Croes;J A Jansen et al.Contact guidance of rat fibroblasts on various implant materials[J].Journal of Biomedical Materials Research,1999,47(02):204-212. |
| [7] | Piao Dongxu;Chen Xiaodong;Mao Lijiang.Study on nerve cell affinity of polymer hydrogel films[A].Chengdu,CHIna,1997 |
| [8] | T Suzuki;Y Mizushima .Characterization of silica-chitosan complex membrane and their relationships to the characteristics of growth and adhesiveness of L-929 cells cultured on the biomembrane[J].Journal of Fermentation and Bioengineering,1997,84(02):128-132. |
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