以静电法通过高压成型装置制备了海藻酸钙-几丁聚糖微胶囊,重点考察了海藻酸钠浓度、凝胶化时间、成膜前冲洗液的种类、几丁聚糖溶液的pH值对微囊形态与粒径的影响.实验结果表明,与生理盐水、甘露醇及直接成膜相比,成膜前采用蒸馏水冲洗胶珠制备出的微囊大小均匀、表面光洁、球形度好;几丁聚糖溶液pH值对微囊形态,甚至膜强度有很大的影响,应根据实际应用需要选取适当的pH值,初步探讨了微囊的控制释放性能.
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