亲和超滤技术是把亲和层析的高选择性和超滤技术的高处理能力相结合的一种新型能大规模进行生物特征物质分离提纯的技术.简要介绍了亲和超滤技术的原理和特征,详细介绍了亲和超滤技术在生物工程和制药工程上的应用.随着亲和超滤技术的发展,应用领域将会不断扩大,将会极大地推动热敏物质(蛋白质、酶、维生素、中草药等)和分子量相近物质(同分异构体、同系物等)分离技术的发展.
参考文献
| [1] | Romero J.;Zydney AL. .Affinity ultrafiltration: Effects of ligand binding on selectivity and process optimization[J].Biotechnology and Bioengineering,2002(3):256-265. |
| [2] | Powers J D;Kilpatrick P K;Carbonell R G .Trypsin purification by affinity binding to small unilamellar liposomes[J].Biotechnology and Bioengineering,1990,36:506-519. |
| [3] | Luong J H;Male K B;Nguyen A L .Affinity process for trypsin purification and stabilization[P].US 4973554,1990-11-27. |
| [4] | Mattiasson B;Ling T G I.Ultrafiltration affinity purification[A].New York and Basel:Mareel Dekker,1986:99-114. |
| [5] | Herak D C;Merrill E W .Affinity cross-floe filtration:experimental and modeling work using the system of HAS and Cibacron Blue-agarose[J].Biotechnology Progress,1989,5(01):9-17. |
| [6] | Powers J D;Kilpartrick P K;Carbonell R G .Protein purification by affinity binding to unilamellar vesicles[J].Biotechnology and Bioengineering,1989,33:173-182. |
| [7] | Hubert P;Dellacherie E .Use of water-soluble biospecific polymers for the purification of proteins[J].Journal of Chromatography,1980,184(03):325-333. |
| [8] | Male K B;Nguyen A L;Luong J H T .Isolation of urokinase by affinity ultrafiltration[J].Biotechnology and Bioengineering,1990,35(01):87-93. |
| [9] | Luong J H T;Male K B;Nguyen A L .A continuous affinity ultrafiltration process for trypsin purification[J].Biotechnology and Bioengineering,1988,31(06):516-520. |
| [10] | 马贵斌;颜叙秀;杨频 等.金属离子与伴刀豆球蛋白A刺激细胞作用的关系研究[J].山西大学学报(自然科学版),1995,18(02):176-179. |
| [11] | Mattiasson B;Ramstorp M .Ultrafiltration affinity purification[J].Annals of the New York Academy of Sciences,1983,413:307-309. |
| [12] | Luong J H T;Male K B;Nguyen A L .Synthesis and characterization of a water-soluble affinity polymer for trypsin purification[J].Biotechnology and Bioengineering,1988,31:439-446. |
| [13] | 胡梁言;阮康成 .胰蛋白酶与ANS的相互作用[J].中国生物化学与分子生物学报,1998,14(05):567-572. |
| [14] | 肖厚荣;王小葵;宋扬 .胰蛋白酶固定化技术研究[J].合肥工业大学学报(自然科学版),1999,22:94-98. |
| [15] | Powers J D;Kilpatrick P K;Carbonell R G .Trypsin purification by affinity binding to small unilamellar liposomes[J].Biotechnology and Bioengineering,1990,36:506-519. |
| [16] | S.Poncet... .Enantiomeric separation of tryptophan by ultrafiltration using the BSA solution system[J].Separation Science and Technology,1997(12):2029-2038. |
| [17] | Garnier F;Randon J;Rocca J L .Enantiomeric separation by ultrafiltration:Complexation mechanism of tryptophan analogs to bovine serum albumin[J].Separation and Purification Technology,1999,16:243-250. |
| [18] | Overdevest P E M;Kurentjes J T F;Vander P A.Resolution of enantiomers using enantioselective micelles in ultrafiltration systems[A].,2000:123-138. |
| [19] | Jonathan Romero;Andrew L. Zydney .Chiral separations using ultrafilration with a stereoselective binding agent[J].Separation Science and Technology,2001(7):1575-1594. |
| [20] | Geiger J R;Trotz S I .Method and kit for separating double-stranded nucleic acid from a single-stranded/double-stranded mixture of nucleic acids[P].US 5034314,1991-07-23. |
| [21] | Huang E Z .Affinity ultrafiltration assay for transferase activity[P].US 5869275,1999-02-09. |
| [22] | Romero J;Zydney A L .pH and salt effects on chiral separation using affinity ultrafitration[J].Desalination,2002,148:159-164. |
| [23] | Luong J H T;Male K B;Nguyen A L et al.Mathematical modeling of affinity ultrafiltration[J].Biotechnology and Bioengineering,1988,32:451-459. |
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