以生物医用球形雾化钛粉为原料,碳酸氢铵做造孔剂,采用放电等离子烧结(SPS)技术制备了生物医用多孔钛块体材料.采用XRD、SEM分别对所制备的多孔钛的物相组成、微观形貌进行分析,并研究了多孔钛的力学性能及成骨细胞在其表面的粘附生长情况.结果表明:通过调节造孔剂添加量、控制烧结工艺可制备孔隙率为50.3%～70.5%、孔径为100～300μm的多孔钛,其力学性能(抗压强度为24.40～68.96MPa、弹性模量为1.010～1.287GPa)与人体松质骨相匹配.与SD大鼠成骨细胞的联合培养结果表明,该材料的粗糙表面和多孔结构可粘附生长成骨细胞,具有良好的生物相容性.
参考文献
| [1] | Ryan G;Pandit A;Apatsidis DP .Fabrication methods of porous metals for use in orthopaedic applications.[J].Biomaterials,2006(13):2651-2670. |
| [2] | Takemoto M;Fujibayashi S;Neo M;Suzuki J;Kokubo T;Nakamura T .Mechanical properties and osteoconductivity of porous bioactive titanium[J].Biomaterials,2005(30):6014-6023. |
| [3] | Ik-Hyun Oh;Naoyuki Nomura;Naoya Masahashi;Shuji Hanada .Mechanical properties of porous titanium compacts prepared by powder sintering[J].Scripta materialia,2003(12):1197-1202. |
| [4] | 李伯琼;陆兴;侯健;滕颖丽 .烧结多孔钦的显微组织和孔隙特征[J].功能材料,2007,38(A05):1762-1764. |
| [5] | C.E. Wen;M. Mabuchi;Y. Yamada .Processing of biocompatible porous Ti and Mg[J].Scripta materialia,2001(10):1147-1153. |
| [6] | Z. Esen;S. Bor .Processing of titanium foams using magnesium spacer particles[J].Scripta materialia,2007(5):341-344. |
| [7] | 邹鹑鸣,张二林,曾松岩.纤维烧结多孔钛及其表面生长仿生Ca-P涂层[J].稀有金属材料与工程,2007(08):1394-1397. |
| [8] | 李虎,虞奇峰,张波,王辉,范红松,张兴栋.浆料发泡法制备生物活性多孔钛及其性能[J].稀有金属材料与工程,2006(01):154-157. |
| [9] | N. G. D. Murray;D. C. Dunand .Microstructure evolution during solid-state foaming of titanium[J].Composites science and technology,2003(16):2311-2316. |
| [10] | Yasumasa Chino;David C. Dunand .Directionally freeze-cast titanium foam with aligned, elongated pores[J].Acta materialia,2008(1):105-113. |
| [11] | LI Yan,GUO Zhimeng,HAO Junjie,REN Shubin.Porosity and mechanical properties of porous titanium fabricated by gelcasting[J].稀有金属（英文版）,2008(03):282-286. |
| [12] | Se-Won Yook;Byung-Ho Yoon;Hyoun-Ee Kim;Young-Hag Koh;Yong-Sik Kim .Porous titanium (Ti) scaffolds by freezing TiH_2/camphene slurries[J].Materials Letters,2008(30):4506-4508. |
| [13] | 李众利,王岩,张国强,肖俊.新型三维连通多孔钛的制备及特性[J].生物骨科材料与临床研究,2007(01):1-4. |
| [14] | CACHINHO SCP;CORREIA RN .Titanium porous scaffolds from precursor powders:rheological optimization of Til-12 slurries[J].Powder Technology,2007,178(02):109-113. |
| [15] | Nicula R;Luthen F;Stir M;Nebe B;Burkel E .Spark plasma sintering synthesis of porous nanocrystalline titanium alloys for biomedical applications.[J].Biomolecular engineering,2007(5):564-567. |
| [16] | 马垚,周张健,姚伟志,宋书香,葛昌纯.放电等离子烧结（SPS）制备金属材料研究进展[J].材料导报,2008(07):60-64. |
| [17] | 谭训香,谭远超,姜红江,苏金平,韩海霞.成人成骨细胞与多孔钛联合培养观察[J].生物骨科材料与临床研究,2007(04):5-7. |
| [18] | 夏露,鲜苏琴,王培志,梁星,杨晓喻,张其翼.多孔海绵状纯钛种植材料对成骨细胞生长的影响[J].口腔颌面修复学杂志,2005(03):179-181. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%