通过电化学和分子印迹技术,在金基底表面成功制备出基于三维纳米金膜修饰的双酚 A(BPA)分子印迹传感器电极.扫描电镜、透射电镜表征和电化学分析结果表明,电化学沉积法可以使纳米金规则成粒,并均匀成膜；纳米金膜使电极表面具备三维结构；纳米金颗粒(AuNPs)可以在分子印迹聚合物(MIPs)中形成内镶嵌结构,使电极表面电导率显著增高.在对 BPA 的检测中,MIPs-AuNPs-Au 电极的响应信号强度约是 MIPs-Au 电极的2．6倍,检测限为1．47×10-8 mol/L.而且,MIPs-AuNPs-Au 电极具有良好的选择性与稳定性.
The gold nanoparticles (AuNPs)modified molecularly imprinted polymers (MIPs)sensing electrode towards bisphenol A has been made by electrochemical methods and molecular imprinting technique on the sur-face of the gold electrode substrate.SEM,TEM and electrochemical analysis were employed to characterize the films on electrode.The results show that the electrochemical deposition method can make the gold nanoparticles grow regularly and the obtained film uniform.AuNPs modified Au electrode has a three-dimensional structure on the surface,and part of gold nanoparticles can be found within the mosaic structure in the MIPs,which in-creases the surface conductivity of the electrode significantly.The signals response to bisphenol A show that the MIP-AuNPs-Au electrode has a 2.63 times higher response compared to the MIPs-Au electrode and its detection limit was 1.47×10 -8 mol/L in detecting bisphenol A.Besides,the MIPs-AuNPs-Au electrode has a good selec-tivity towards bisphenol A and favorable stability.
参考文献
| [1] | Vandenberg LN;Hauser R;Marcus M;Olea N;Welshons WV .Human exposure to bisphenol A (BPA).[J].Reproductive toxicology,2007(2):139-177. |
| [2] | Ya Ting Liu;Jian Deng;Xi Lin Xiao;Li Ding;Ya Li Yuan;Hui Li;Xiu Ting Li;Xiao Na Yan;Li Li Wang .Electrochemical sensor based on a poly(para-aminobenzoic acid) film modified glassy carbon electrode for the determination of melamine in milk[J].Electrochimica Acta,2011(12):4595-4602. |
| [3] | Kaiguang Yang;Jiaojiao Ma;Hui Zhou .Molecularly imprinted porous polysulfone particles for the binding and recognition of bisphenol A[J].Desalination: The International Journal on the Science and Technology of Desalting and Water Purification,2009(1/3):232-245. |
| [4] | Taher Alizadeh;Somaye Amjadi .Preparation of nano-sized Pb~(2+) imprinted polymer and its application as the chemical interface of an electrochemical sensor for toxic lead determination in different real samples[J].Journal of hazardous materials,2011(1/3):451-459. |
| [5] | Yaqiong Wang;Yuanyuan Yang;Lan Xu;Jin Zhang .Bisphenol A sensing based on surface molecularly imprinted, ordered mesoporous silica[J].Electrochimica Acta,2011(5):2105-2109. |
| [6] | Haixia Fan;Yan Li;Dan Wu.Electrochemical bisphenol A sensor based on N-doped graphene sheets[J].Analytica chimica acta,2012:24-28. |
| [7] | 张学骜,吴文健,刘长利,王建方.自组装制备有机/无机层状复合材料[J].功能材料,2005(11):1645-1650. |
| [8] | Huang, J.;Zhang, X.;Liu, S.;Lin, Q.;He, X.;Xing, X.;Lian, W. .Electrochemical sensor for bisphenol A detection based on molecularly imprinted polymers and gold nanoparticles[J].Journal of Applied Electrochemistry,2011(11):1323-1328. |
| [9] | Wang, Z.;Li, H.;Chen, J.;Xue, Z.;Wu, B.;Lu, X. .Acetylsalicylic acid electrochemical sensor based on PATP-AuNPs modified molecularly imprinted polymer film[J].Talanta: The International Journal of Pure and Applied Analytical Chemistry,2011(3):1672-1679. |
| [10] | Michael Riskin;Yaniv Ben-Amram;Ran Tel-Vered;Vladimir Chegel;Joseph Almog;Itamar Willner .Molecularly Imprinted Au Nanoparticles Composites on Au Surfaces for the Surface Plasmon Resonance Detection of Pentaerythritol Tetranitrate, Nitroglycerin, and Ethylene Glycol Dinitrate[J].Analytical chemistry,2011(8):3082-3088. |
| [11] | Michael Riskin;Ran Tel-Vered;Oleg Lioubashevski;Itamar Willner .Ultrasensitive Surface Plasmon Resonance Detection of Trinitrotoluene by a Bis-aniline-Cross-Linked Au Nanoparticles Composite[J].Journal of the American Chemical Society,2009(21):7368-7378. |
| [12] | Riskin M;Tel-Vered R;Bourenko T;Granot E;Willner I .Imprinting of molecular recognition sites through electropolymerization of functionalized au nanoparticles: Development of an electrochemical TNT sensor based on pi-donor-acceptor interactions[J].Journal of the American Chemical Society,2008(30):9726-9733. |
| [13] | Huang, J.;Zhang, X.;Liu, S.;Lin, Q.;He, X.;Xing, X.;Lian, W.;Tang, D. .Development of molecularly imprinted electrochemical sensor with titanium oxide and gold nanomaterials enhanced technique for determination of 4-nonylphenol[J].Sensors and Actuators, B. Chemical,2011(2):292-298. |
| [14] | Lian W J;Huang J D;Yu J H et al.A molecularly im-printed sensor based on b-cyclodextrin incorporated mul-tiwalled carbon nanotube and gold nanoparticles-polyam-ide amine dendrimer nanocomposites combining with wa-ter-soluble chitosan derivative for the detection of chlor-tetracycline[J].FOOD CONTROL,2012,26(2):620-627. |
| [15] | Saha, K.;Agasti, S.S.;Kim, C.;Li, X.;Rotello, V.M. .Gold nanoparticles in chemical and biological sensing[J].Chemical Reviews,2012(5):2739-2779. |
| [16] | 谭忠印;周丹红.电化学分析原理及技术[M].大连:辽宁师范大学出版社,2001 |
| [17] | Shu-feng Liu;Xiao-hong Li;Yun-chao Li;Yong-fang Li;Jin-ru Li;Long Jiang .The influence of gold nanoparticle modified electrode on the structure of mercaptopropionic acid self-assembly monolayer[J].Electrochimica Acta,2005(3):427-431. |
| [18] | Li, H.;Xie, C.;Li, S.;Xu, K. .Electropolymerized molecular imprinting on gold nanoparticle-carbon nanotube modified electrode for electrochemical detection of triazophos[J].Colloids and Surfaces, B. Biointerfaces,2012(1):175-181. |
| [19] | Li X;Chen Y;Huang X .Electrochemical behavior of neomycin at DNA-modified gold electrodes[J].Journal of Inorganic Biochemistry: An Interdisciplinary Journal,2007(6):918-924. |
| [20] | 李景虹.自组装膜电化学[M].北京:高等教育出版社,2002 |
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