天然产物体系复杂,尤其是一些活性成分含量较低,采用一般的方法对其进行分离富集难度较大.分子印迹聚合物具有良好的亲和性和专一的选择,将分子印迹固相萃取技术应用于天然药物资源样品前处理过程,能够选择性地分离富集复杂基质中的目标成分.本文对近几年分子印迹固相萃取技术在天然产物有效成分分离分析中的应用进行了总结,分析物包括黄酮类、多元酚类、生物碱类、有机酸类、苯丙素类、萜类以及其他一些类型的生物活性成分.
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