Ugi反应是由1分子醛或酮、1分子胺、1分子异腈和1分子羧酸4个组分通过缩聚反应生成α-酰氨基酰胺类化合物的反应.具有反应条件温和、产率高和原子经济性好等特点.该反应还可与Suzuki、Heck和Smiles等经典反应偶联,使得其在天然产物合成方面得到越来越多的关注.本文概括总结了近几十年来Ugi反应在一些天然产物合成中的应用.
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