将Mg和Mg-Ca合金进行热一自组装单分子膜表面改性,并将其试样浸泡在SBF中和植入动物体内进行比较试验,用LKI198B测试腐蚀电流密度,用原子吸收光谱测定溶液中的镁离子浓度,测量试样的质量和溶液pH值的变化,用SEM、XRD,FTIR、EDS等分析其表面形貌、物相组成和成分变化,研究了材料的腐蚀降解特性.结果表明,热自组装膜改善了镁基生物材料的腐蚀抗力和生物活性.纯Mg的腐蚀速率由0.11 mm/y下降到0.05 ram/y,Mg-Ca合金的腐蚀速率由0.38 mm/y下降到0.32 mm/y.植入动物12周后,直径的减小由0.97 mm下降到0.20 mm,界面新类骨质层厚度由2.56 mm增加到3.14 mm.
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