利用2-(甲基丙烯酰氧基)乙基-2-(三甲基氨基)乙基磷酸酯(MPC)与316L不锈钢表面上γ-氨基丙基三乙氧基硅烷(KH550)的Michael加成反应,将MPC化学接枝到不锈钢的表面.修饰表面的XPS结果证实了MPC的成功接枝,表明在不锈钢表面构建了仿细胞膜表面.体外血小板粘附实验显示,修饰表面具有明显阻抗血小板的粘附、聚集和激活性能,并具有良好的血液相容性.
参考文献
| [1] | S.Windecker,I.Mayer,G.De Pasquale,W.Maier,O.Dirsch,P.De Groot,Y.P.Wu,G.Noll,B.Leskosek,B.Meier,O.M.Hess,Circulation,104,928(2001). |
| [2] | J.Hong,A.Azens,K.N.Ekdahl,C.G.Granqvist,B.Nilsson,Biomaterials,26,1397(2005) |
| [3] | J.A.Hayward,D.Chapman,Biomaterials,5,135(1984) |
| [4] | K.Ishihara,H.Nomura,T.Mihara,K.Kurita,Y.Iwasaki,N.Nakabayashi,Journal of Biomedical Materials Research,39,323(1998) |
| [5] | T.Ueda,H.Oshida,K.Kurita,K.Ishihara,N.Nakabayshi,Polym.Journal,24,1259(1992) |
| [6] | J.M.Xu,Y.L.Yuan,B.Shan,J.Shen,S.C.Lin,Colloids and Surfaces B-Biointerfaces,30,215(2003) |
| [7] | K.Kim,C.Kim,Y.Byun,Journal of Biomaterials SciencePolymer Edition,14,887(2003) |
| [8] | K.Ishihara,H.Hanyuda,N.Nakabayashi,Biomaterials,16,873(1995) |
| [9] | R.J.Russell,K.Sirkar,M.V.Pishko,Langmuir,16,4052(2000) |
| [10] | D.A.Wang,J.Ji,C.Y.Gao,G.H.Yu,L.X.Feng,Biomaterials,22,1549(2001) |
| [11] | L.Zhang,Z.S.Bo,B.Zhao,Y.Q.Wu,X.Zhang,J.C.Shen,Thin Solid Films,329,221(1998) |
| [12] | S.L.Willis,J.L.Court,R.P.Redman,J.H.Wang,S.W.Leppard,V.J.O'Byrne,S.A.Small,A.L.Lewis,S.A.Jones,P.W.Stratford,Biomaterials,22,3261(2001) |
| [13] | V.A.Tegoulia,W.S.Rao,A.T.Kalambur,J.R.Rabolt,S.L.Cooper,Langmuir,17,4396(2001) |
| [14] | J.M.Grunkemeier,W.B.Tsai,T.A.Horbett,Journal of Biomaterials Science-Polymer Edition,12,1(2001) |
| [15] | M.Franco,P.F.Nealey,S.Campbell,A.I.Teixeira,C.J.Murphy,Journal of Biomedical Materials Research,52,261(2000) |
| [16] | T.Ueda,A.Watanabe,K.Ishihara,N.Nakabayashi,J.Biomater.Sci.Polym.Edition,3,185(1991) |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%