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关节置换术是目前治疗关节疾病最直接、有效的手段,随着国民经济的增长,人工关节在我国的需求量不断增加。介绍了常见人工关节的类型及特点,以及目前用于提高人工关节摩擦副表面耐磨损性及耐腐蚀性的方法,通过比较发现,类金刚石(DLC)薄膜在提高人工关节耐磨损、耐腐蚀性能方面具有更好的应用前景。阐述了DLC薄膜结构、性能及其制备方法,并结合目前DLC薄膜在人工关节摩擦配副表面改性中应用所面临的主要问题,介绍了目前用于降低DLC薄膜内应力、增加DLC薄膜/基体结合力的方法。最后,针对 DLC 薄膜应用于人工关节摩擦配副表面改性中存在的缝隙腐蚀及结合失效问题,并结合人工关节体内服役环境特点,提出了利用金属离子催化人工关节摩擦配副表面吸附蛋白的变性、分解,形成致密生物薄膜,对DLC薄膜的磨痕和缺陷进行修复的思想,展望了新型DLC薄膜在人工关节表面改性中的应用前景。

Arthroplasty is the most effective method for the treatment of joint disease in clinical practice, and there are in-creasing needs for artificial joints with the development of national economy. There are three types of artificial joints in clinical practice. Lots of methods have been used to enhance the wear and corrosion resistance of artificial joints. Diamond-like carbon (DLC) film has low friction coefficient, high wear resistance and good biocompatibility, which has been used to improve the wear and corrosion resistance of artificial joints. But the clinical use of DLC coated artificial joint is unsatisfying. This paper discussed the reasons for DLC failure in vivo. Metal doping DLC film or multilayer DLC film could lower the internal stress, improve the adhesion and postpone the DLC film failure. Concerning the service environment of artificial joints, the crevice corrosion and adhesion of DLC film, we proposed to control the formation of biofilm on the surface of the artificial joints through the use of metal ions to promote protein denaturation and decomposition. And this biofilm could prevent corrosion me-dium (Cl-, PO43-) from penetrating into the interface of film and substrate. So the crevice and interface corrosion would be re-strained. And the lifetime of DLC film would be prolonged.

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