制备了用于骨科的挤压态 Mg?Sn?Ca 合金，并应用金相显微镜、扫描电子显微镜、X 射线衍射仪、拉伸测试、浸泡测试和电化学测试等仪器和方法对其进行研究。结果表明：当锡添加量为1%，钙含量从0.2%增加到0.5%时，挤压态 Mg?Sn?Ca 合金的显微组织变得均匀，力学性能增加，耐腐蚀性提高。钙含量进一步增加到1.5%时，合金的强度增加，但伸长率和耐腐蚀性降低。在钙含量为0.5%的合金中，锡的含量从1%增加到3%时，合金的最大抗拉强度增加，耐腐蚀性降低。当锡含量为2%时，合金呈现最低的屈服强度和伸长率。挤压态 Mg?Sn?Ca合金的这些行为受到 Sn/Ca 比率的控制。分析表明挤压态 Mg?1Sn?0.5Ca 合金有潜力作为可降解骨科植入体。
The as-extruded Mg?Sn?Ca alloys were prepared and investigated for orthopedic applications via using optical microscopy, scanning electron microscopy, X-ray diffraction, as well as tensile, immersion and electrochemical tests. The results showed that, with the addition of 1% Sn and the Ca content of 0.2%?0.5%, the microstructure of the as-extruded Mg?Sn?Ca alloys became homogenous, which led to increased mechanical properties and improved corrosion resistance. Further increase of Ca content up to 1.5% improved the strength, but deteriorated the ductility and corrosion resistance. For the alloy containing 0.5% Ca, when the Sn content increased from 1% to 3%, the ultimate tensile strength increased with a decreased corrosion resistance, and the lowest yield strength and ductility appeared with the Sn content of 2%. These behaviors were determined by Sn/Ca mass ratio. The analyses showed that as-extruded Mg?1Sn?0.5Ca alloy was promising as a biodegradable orthopedic implant.
参考文献
| [1] | Nan Li;Yufeng Zheng.Novel Magnesium Alloys Developed for Biomedical Application: A Review[J].材料科学技术（英文版）,2013(6):489-502. |
| [2] | Staiger MP;Pietak AM;Huadmai J;Dias G.Magnesium and its alloys as orthopedic biomaterials: A review[J].Biomaterials,20069(9):1728-1734. |
| [3] | Seyed Morteza Ghaffari SHAHRI;Mohd Hasbullah IDRIS;Hassan JAFARI;Babak GHOLAMPOUR;Mahtab ASSADIAN.固溶处理对可生物降解Mg-6Zn合金腐蚀性能的影响[J].中国有色金属学报（英文版）,2015(05):1490-1499. |
| [4] | Z.S.SEYEDRAOUFI;Sh.MIRDAMADI.脉冲电沉积涂覆纳米羟基磷灰石的多孔Mg-Zn支架材料的体外生物降解能力和生物相容性[J].中国有色金属学报（英文版）,2015(12):4018-4027. |
| [5] | Witte F;Fischer J;Nellesen J;Crostack HA;Kaese V;Pisch A;Beckmann F;Windhagen H.In vitro and in vivo corrosion measurements of magnesium alloys[J].Biomaterials,20067(7):1013-1018. |
| [6] | Witte F;Kaese V;Haferkamp H;Switzer E;Meyer Lindenberg A;Wirth CJ;Windhagen H.In vivo corrosion of four magnesium alloys and the associated bone response.[J].Biomaterials,200517(17):3557-3563. |
| [7] | Witte F;Fischer J;Nellesen J;Vogt C;Vogt J;Donath T;Beckmann F.In vivo corrosion and corrosion protection of magnesium alloy LAE442.[J].Acta biomaterialia,20105(5):1792-1799. |
| [8] | El Rahman SS.Neuropathology of aluminum toxicity in rats (glutamate and GABA impairment).[J].Pharmacological research: The official journal of The Italian Pharmacological Society,20033(3):189-194. |
| [9] | Gu X;Zheng Y;Cheng Y;Zhong S;Xi T.In vitro corrosion and biocompatibility of binary magnesium alloys.[J].Biomaterials,20094(4):484-498. |
| [10] | Ilich JZ;Kerstetter JE.Nutrition in bone health revisited: a story beyond calcium.[J].Journal of the American College of Nutrition,20006(6):715-737. |
| [11] | Li Z;Gu X;Lou S;Zheng Y.The development of binary Mg-Ca alloys for use as biodegradable materials within bone.[J].Biomaterials,200810(10):1329-1344. |
| [12] | Hamid Reza Bakhsheshi Rad;Mohd Hasbullah Idris;Mohammed Rafiq Abdul Kadir;Saeed Farahany.Microstructure analysis and corrosion behavior of biodegradable Mg-Ca implant alloys[J].Materials & design,2012Jan.(Jan.):88-97. |
| [13] | Woo-Cheol Kim;Jung-Gu Kim;Ji-Young Lee;Hyun-Kwang Seok.Influence of Ca on the corrosion properties of magnesium for biomaterials[J].Materials Letters,200825(25):4146-4148. |
| [14] | Yizao Wan;Guangyao Xiong;Honglin Luo;Fang He;Yuan Huang;Xiaoshong Zhou.Preparation and characterization of a new biomedical magnesium-calcium alloy[J].Materials & design,200810(10):2034-2037. |
| [15] | Erdmann N;Angrisani N;Reifenrath J;Lucas A;Thorey F;Bormann D;Meyer Lindenberg A.Biomechanical testing and degradation analysis of MgCa0.8 alloy screws: a comparative in vivo study in rabbits.[J].Acta biomaterialia,20113(3):1421-1428. |
| [16] | Erlin Zhang;Lei Yang.Microstructure, mechanical properties and bio-corrosion properties of Mg–Zn–Mn–Ca alloy for biomedical application[J].Materials Science & Engineering, A. Structural Materials: Properties, Misrostructure and Processing,20081/2(1/2):111-118. |
| [17] | Yu Sun;Baoping Zhang;Yin Wang;Lin Geng;Xiaohui Jiao.Preparation and characterization of a new biomedical Mg-Zn-Ca alloy[J].Materials & design,2012Feb.(Feb.):58-64. |
| [18] | Mitsuo Niinomi.Recent research and development in titanium alloys for biomedical applications and healthcare goods[J].Science and technology of advanced materials,20035(5):445-454. |
| [19] | Wenjin Zhang;Meiheng Li;Qian Chen;Wangyu Hu;Wenmei Zhang;Wang Xin.Effects of Sr and Sn on microstructure and corrosion resistance of Mg-Zr-Ca magnesium alloy for biomedical applications[J].Materials & design,2012Aug.(Aug.):379-383. |
| [20] | G. Nayyeri;R. Mahmudi.The microstructure and impression creep behavior of cast, Mg–5Sn–xCa alloys[J].Materials Science & Engineering, A. Structural Materials: Properties, Misrostructure and Processing,20107/8(7/8):2087-2098. |
| [21] | T. ABU LEIL;N. HORT;W. DIETZEL;C. BLAWERT;Y. HUANG;K. U. KAINER;K. P. RAO2.Microstructure and corrosion behavior of Mg-Sn-Ca alloys after extrusion[J].中国有色金属学会会刊（英文版）,2009(01):40-44. |
| [22] | H.J. Zhang;D.F. Zhang;C.H. Ma;S.F. Guo.Improving mechanical properties and corrosion resistance of Mg-6Zn-Mn magnesium alloy by rapid solidification[J].Materials Letters,2013Feb.1(Feb.1):45-48. |
| [23] | Zhang, EL;Yin, DS;Xu, LP;Yang, L;Yang, K.Microstructure, mechanical and corrosion properties and biocompatibility of Mg-Zn-Mn alloys for biomedical application[J].Materials science & engineering, C. Biomimetic and supramolecular systems,20093(3):987-993. |
| [24] | Chenglong Liu;Yunchang Xin;Xiubo Tian.Degradation susceptibility of surgical magnesium alloy in artificial biological fluid containing albumin[J].Journal of Materials Research,20077(7):1806-1814. |
| [25] | Xiaobo Zhang;Guangyin Yuan;Jialin Niu;Penghuai Fu;Wenjiang Ding.Microstructure, mechanical properties, biocorrosion behavior, and cytotoxicity of as-extruded Mg-Nd-Zn-Zr alloy with different extrusion ratios.[J].Journal of the mechanical behavior of biomedical materials,2012:153-162. |
| [26] | Rao, K.P.;Prasad, Y.V.R.K.;Suresh, K.;Hort, N.;Kainer, K.U..Hot deformation behavior of Mg-2Sn-2Ca alloy in as-cast condition and after homogenization[J].Materials Science & Engineering, A. Structural Materials: Properties, Misrostructure and Processing,2012:444-450. |
| [27] | Cai, S.;Lei, T.;Li, N.;Feng, F..Effects of Zn on microstructure, mechanical properties and corrosion behavior of Mg-Zn alloys[J].Materials science & engineering, C. Biomimetic and supramolecular systems,20128(8):2570-2577. |
| [28] | Zhang S;Zhang X;Zhao.Research on an Mg-Zn alloy as a degradable biomaterial.[J].Acta biomaterialia,20102(2):626-640. |
| [29] | BobbyKannan,M.;SinghRaman,R.K..A mechanistic study of in vitro degradation of magnesium alloy using electrochemical techniques[J].Journal of biomedical materials research, Part A,20103(3):1050-1055. |
| [30] | F. ZUCCHI;V. GRASSI;A. FRIGNANI.Electrochemical behaviour of a magnesium alloy containing rare earth elements[J].Journal of Applied Electrochemistry,20062(2):195-204. |
| [31] | K.D. Ralston;N. Birbilis.Effect of Grain Size on Corrosion A Review[J].Corrosion: The Journal of Science and Engineering,20107(7):075005:1-075005:13. |
| [32] | G.R. Argade;S.K. Panigrahi;R.S. Mishra.Effects of grain size on the corrosion resistance of wrought magnesium alloys containing neodymium[J].Corrosion Science: The Journal on Environmental Degradation of Materials and its Control,2012may(may):145-151. |
| [33] | Ming-Chun Zhao;Ming Liu;Guangling Song;Andrej Atrens.Influence of the β-phase morphology on the corrosion of the Mg alloy AZ91[J].Corrosion Science: The Journal on Environmental Degradation of Materials and its Control,20087(7):1939-1953. |
| [34] | Guongling Song;Andrej Atrens.Understanding Magnesium Corrosion: A Framework for Improved Alloy Performance[J].Advanced Engineering Materials,200312(12):837-858. |
| [35] | Zhao, Chaoyong;Pan, Fusheng;Zhao, Shuang;Pan, Hucheng;Song, Kai;Tang, Aitao.Preparation and characterization of as-extruded Mg-Sn alloys for orthopedic applications[J].Materials & design,2015Apr.(Apr.):60-67. |
| [36] | Zhao, Chaoyong;Pan, Fusheng;Zhao, Shuang;Pan, Hucheng;Song, Kai;Tang, Aitao.Microstructure, corrosion behavior and cytotoxicity of biodegradable Mg-Sn implant alloys prepared by sub-rapid solidification[J].Materials science & engineering, C. Materials for Biogical applications,2015:245-251. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%