Titanium rods were processed into implant samples with cavity and groove in which was filled with HAP/β-TCP porous osteoconduction composite materials in order to increase the mechanical stability of the implant in vivo. The phase compositions of the composite was characterized by X-ray diffraction (XRD) and scanning electron microscopy(SEM). Histological evaluation showed that the biogradable composite could enhanced the ability of new bone formation. The composite can conduct new bone tissue growing into the cavities gradually after implanted into animal, and then achieve mechanical fixation. The filling biogradable compound exhibited excellent biocompatibility, which combined with the new bone tissues tightly without inflammation and loosing.
参考文献
| [1] | Peter Heinl;Carolin Korner;Robert F. Singer .Selective Electron Beam Melting of Cellular Titanium: Mechanical Properties[J].Advanced Engineering Materials,2008(9):882-888. |
| [2] | G. Goller;F.N. Oktar;L.S. Ozyegin .Plasma-sprayed human bone-derived hydroxyapatite coating effective and reliable[J].Materials Letters,2004(21):2599-2604. |
| [3] | Takemoto M;Fujibayashi S;Neo M;Suzuki J;Kokubo T;Nakamura T .Mechanical properties and osteoconductivity of porous bioactive titanium[J].Biomaterials,2005(30):6014-6023. |
| [4] | M. H. Fathi;A. Doostmohammadi .Bioactive glass nanopowder and bioglass coating for biocompatibility improvement of metallic implant[J].Journal of Materials Processing Technology,2009(3):1385-1391. |
| [5] | Liang H;Shi B;Fairchild A;Cale T .Applications of plasma coatings in artificial joints: an overview[J].Vacuum: Technology Applications & Ion Physics: The International Journal & Abstracting Service for Vacuum Science & Technology,2004(3/4):317-326. |
| [6] | Honglian DAI,Xianying CAO,Haichen SHAO,Chunhua SHEN,Shipu LI.EPMA Study of the Interface of β-Tricalcium Phosphate Ceramics in Vivo[J].材料科学技术学报（英文版）,2004(06):657-661. |
| [7] | Xiufeng Xiao;Rongfang Liu;Qiongyu Huang .Preparation and characterization of nano-hydroxyapatite/polymer composite scaffolds[J].Journal of Materials Science. Materials in Medicine,2008(11):3429-3435. |
| [8] | Ning C;Zhou Y .Correlations between the in vitro and in vivo bioactivity of the Ti/HA composites fabricated by a powder metallurgy method.[J].Acta biomaterialia,2008(6):1944-1952. |
| [9] | Wu,F;Wei,J;Guo,H;Chen,F;Hong,H;Liu,C .Self-setting bioactive calcium-magnesium phosphate cement with high strength and degradability for bone regeneration.[J].Acta Biomaterialia,2008(6):1873-1884. |
| [10] | Ciapetti G;Ambrosio L;Savarino L;Granchi D;Cenni E;Baldini N;Pagani S;Guizzardi S;Causa F;Giunti A .Osteoblast growth and function in porous poly varepsilon -caprolactone matrices for bone repair: a preliminary study.[J].Biomaterials,2003(21):3815-3824. |
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