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Titanium oxide films were prepared using an anodic oxidation method in sulfuric acid solution on the surface of Ti6Al4V alloy at room temperature. The surface energy was obtained by the measurement of contact angles and the calculation with Owens-Wendt-Kaeble's equation. Ti6Al4V with anodic film after chemical treatment with NaOH aqueous solution showed excellent apatite-forming ability and produced a compact apatite layer covering all the surface of titanium after soaking in three times concentration (SBF x 3) for three days. A bioactive titania-CaP film was obtained on Ti6Al4V. Scanning electron microscopy, X-ray diffraction and Fourier Transform Infra-Red were used to analyze composition changes of the bioactive film. It is concluded that the acceleration of the apatite nucleation on the anodized Ti6Al4V with chemical treatment in a modified simulated body fluid was attributed to the novel surface characteristics and the formation of sodium titanate hydrogel layer during chemical pretreatment. The treatment of Ti6Al4V by anodic oxidation and subsequently in NaOH is a suitable method for providing the metal implant with bone-bonding ability.

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