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The depletion potential between two colloid particles immersed in an associating fluid was investigated by the classical density functional theory for depletion potential proposed by Roth, Evans and Dietrich. An attempt is made to obtain the effects of several factors concerning colloid particles and solvent molecules on the depletion potential, which are the bulk density of solvent, size ratio of colloid particle to solvent, functionality of solvent and its associated energy, and the interaction between colloid particle and solvent.. With the depletion potential under various conditions being presented, it is shown that the effects of these factors on the depletion potential are significant. The results provide some useful clues on regulating the interaction between colloid particles in the related experiments.

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