Pre-strained nanomembranes with four embedded quantum wells (QWs) are rolled up into three-dimensional (3D) tubular QW infrared photodetectors (QWIPs),which are based on the QW intersubband transition (ISBT).A redshift of～0.42 meV in photocurrent response spectra is observed and attributed to two strain contributions due to the rolling of the pre-strained nanomembranes.One is the overall strain that mainly leads to a redshift of～0.5 meV,and the other is the strain gradient which results in a very tiny variation.The blue shift of the photocurrent response spectra with the external bias are also observed as quantum-confined Stark effect (QCSE) in the ISBT.