{"currentpage":1,"firstResult":0,"maxresult":10,"pagecode":5,"pageindex":{"endPagecode":3,"startPagecode":1},"records":[{"abstractinfo":"为了探讨2-巯基苯并噻唑(MBT)的生物降解性,借鉴浮选捕收剂等有机物的生物降解性评价体系,分别采用静置烧瓶筛选试验法、震荡培养法(GB/T 15818-2006)、改良斯特姆法(OECD-301B)3种评价方法首次对MBT的生物降解性进行探讨.结果表明:在静置烧瓶筛选试验法中,MBT在第4周期的生物降解度为4.68％;在震荡培养法中,MBT的8d生物降解度为28.9％;在改良斯特姆法中,MBT的生物降解性指数IB为77.07,相对降解度(DRBD)为35.49％.这3种评价方法得出的结论一致表明MBT属于难生物降解有机物,对微生物有一定毒害作用,抑制微生物的生长.本研究可为MBT的环境行为以及含MBT废水的生物处理技术提供基础资料.","authors":[{"authorName":"许娉婷","id":"3cdf3729-fcbd-400c-91a4-fca155de4b4d","originalAuthorName":"许娉婷"},{"authorName":"<span style=\"color:red\">林伟</span><span style=\"color:red\">雄</span>","id":"75f2e2b9-a29a-4e53-b2ec-f479cbb2b08e","originalAuthorName":"林伟雄"},{"authorName":"孙水裕","id":"39adf0ff-2df9-4d12-b77a-7764fade56fb","originalAuthorName":"孙水裕"},{"authorName":"任杰","id":"af9d47bb-a586-4bc0-98e1-ccd9b15273fd","originalAuthorName":"任杰"},{"authorName":"戴永康","id":"02482ab3-3858-48e3-8ade-699426bbf0e9","originalAuthorName":"戴永康"},{"authorName":"李海宇","id":"63ae4487-7564-4963-8d70-95bf9904c1a9","originalAuthorName":"李海宇"},{"authorName":"徐启智","id":"3b69fe64-360d-4e4b-95a4-9daacb892f95","originalAuthorName":"徐启智"},{"authorName":"庄圣炜","id":"221773ee-c3ae-4315-80aa-156054211df2","originalAuthorName":"庄圣炜"}],"doi":"","fpage":"198","id":"7b216537-deeb-4a81-a11c-cf653fb6fa01","issue":"1","journal":{"abbrevTitle":"ZGYSJSXB","coverImgSrc":"journal/img/cover/ZGYSJSXB.jpg","id":"88","issnPpub":"1004-0609","publisherId":"ZGYSJSXB","title":"中国有色金属学报"},"keywords":[{"id":"4274ce7c-d9a3-4e5d-85b2-e26278c89d0e","keyword":"2-巯基苯并噻唑","originalKeyword":"2-巯基苯并噻唑"},{"id":"4d9bb141-4aed-4cf9-a01c-69466bfd87c1","keyword":"生物降解性","originalKeyword":"生物降解性"},{"id":"3aa84a5a-17f4-4dff-b99e-04839e030303","keyword":"评价","originalKeyword":"评价"},{"id":"5d82cf18-bfcf-4acf-9e07-fd1be621f038","keyword":"动力学","originalKeyword":"动力学"}],"language":"zh","publisherId":"zgysjsxb201701025","title":"2-巯基苯并噻唑的生物降解性评价","volume":"27","year":"2017"},{"abstractinfo":"为了获得高效的有毒选矿药剂浮选废水的处理工艺,率先开展利用膜生物反应器(sMBR)技术来处理含苯胺黑药选矿废水,研究不同水力停留时间和不同进水药剂初始浓度对sMBR系统的处理效果影响,并考察不同进水药剂浓度对系统污泥产生的影响.结果表明:水力停留时间的延长有利于系统的处理效果的提高,经济有效的水力停留时间为3h;高浓度苯胺黑药对系统的COD去除效果有抑制作用,同时对系统污泥的浓度和活性有一定的抑制作用.sMBR在水力停留时间为3h的条件下稳定运行,在此条件下处理不同进水药剂浓度的COD去除率大于80％.","authors":[{"authorName":"<span style=\"color:red\">林伟</span><span style=\"color:red\">雄</span>","id":"7c9c7c15-d5b1-4e15-93c8-9fd4f0204a45","originalAuthorName":"林伟雄"},{"authorName":"许娉婷","id":"2fea7bdc-dd65-4ef8-8f42-d795b46709d8","originalAuthorName":"许娉婷"},{"authorName":"武纯","id":"bb301ca2-125f-4be2-9531-d6b3bb78f808","originalAuthorName":"武纯"},{"authorName":"戴永康","id":"0b8c8488-c2ef-4711-9287-c4f5b81ed40b","originalAuthorName":"戴永康"},{"authorName":"任杰","id":"76488e6a-e6e3-4ce3-ae75-47b0487206d4","originalAuthorName":"任杰"},{"authorName":"孙水裕","id":"ba679f11-8e89-491b-b891-3f997979b137","originalAuthorName":"孙水裕"},{"authorName":"刘敬勇","id":"8661df56-692f-4574-9dd3-19b7a47df48e","originalAuthorName":"刘敬勇"}],"doi":"","fpage":"2461","id":"bc8d9f3e-f5ab-4ac0-aee5-823ea4afae93","issue":"11","journal":{"abbrevTitle":"ZGYSJSXB","coverImgSrc":"journal/img/cover/ZGYSJSXB.jpg","id":"88","issnPpub":"1004-0609","publisherId":"ZGYSJSXB","title":"中国有色金属学报"},"keywords":[{"id":"9fe09bc9-3dd3-4480-8625-ae6e2ac873eb","keyword":"浸没式膜生物反应器","originalKeyword":"浸没式膜生物反应器"},{"id":"abf733ab-505d-4965-8c16-758ddabf690e","keyword":"苯胺黑药浮选废水","originalKeyword":"苯胺黑药浮选废水"},{"id":"af2c11f1-2e54-4253-a08a-768c7e84b3a7","keyword":"水力停留时间","originalKeyword":"水力停留时间"},{"id":"53756e84-3a6a-448c-8969-340f469cbf6d","keyword":"处理效果","originalKeyword":"处理效果"},{"id":"7626eb94-40b6-4b2b-82f0-1fb8343ec564","keyword":"污泥","originalKeyword":"污泥"}],"language":"zh","publisherId":"zgysjsxb201611024","title":"采用浸没式膜生物反应器处理苯胺黑药浮选废水","volume":"26","year":"2016"},{"abstractinfo":"以醋酸去氢表<span style=\"color:red\">雄</span>酮为起始原料,于温度为65～70℃的DMSO-甲苯混合溶剂中,反应时间为22 h,利用二碘酰基苯甲酸(IBX)对醋酸去氢表<span style=\"color:red\">雄</span>酮的选择性脱氢简便高效地合成了曲螺酮关键中间体3β-乙酰氧基-<span style=\"color:red\">雄</span>甾-△4,15-二烯-17-酮;探讨了IBX与醋酸去氢表<span style=\"color:red\">雄</span>酮的摩尔比对目标化合物的收率影响.实验表明.在n(IBX):n(醋酸去氢表<span style=\"color:red\">雄</span>酮)=1.5∶1.0时,目标化合物的收率最佳,达到73%.目标化合物经紫外光谱、红外光谱、核磁共振氢谱、质谱及元素分析测试技术确证了其化学结构.","authors":[{"authorName":"贺诗华","id":"10e09bce-0f1c-4da2-a46e-8f4a52ddc3d0","originalAuthorName":"贺诗华"},{"authorName":"WANG Chun-Ting","id":"bdce8fe1-6816-44fc-be7c-745d0561e9a4","originalAuthorName":"WANG Chun-Ting"}],"doi":"10.3969/j.issn.1000-0518.2008.08.028","fpage":"992","id":"7f557618-a2da-4590-9eaa-731450d12c72","issue":"8","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"443eb0f0-e283-49f5-9eee-85ef2b28b31f","keyword":"醋酸去氢表<span style=\"color:red\">雄</span>酮","originalKeyword":"醋酸去氢表雄酮"},{"id":"531409dd-8d3f-4e1d-a203-959cb2b26fe9","keyword":"IBX","originalKeyword":"IBX"},{"id":"d2f377e1-52cc-4022-b8d4-860fd9e5cfb1","keyword":"β-乙酰氧基-<span style=\"color:red\">雄</span>甾-△5","originalKeyword":"β-乙酰氧基-雄甾-△5"},{"id":"582d52ac-7d46-4c8e-8a6e-2b9faff38d29","keyword":"15-二烯.酮","originalKeyword":"15-二烯.酮"},{"id":"8e8795d5-a2d3-438c-bee5-ba81fc378b71","keyword":"αβ-不饱和羰基甾体","originalKeyword":"αβ-不饱和羰基甾体"},{"id":"b8d1f8c6-e9a5-4a8c-96f0-3982a60608c4","keyword":"中间体","originalKeyword":"中间体"}],"language":"zh","publisherId":"yyhx200808028","title":"用IBX对醋酸去氢表<span style=\"color:red\">雄</span>酮选择性脱氢合成3β-乙酰氧基-<span style=\"color:red\">雄</span>甾-△5,15-二烯-17-酮","volume":"25","year":"2008"},{"abstractinfo":"去氢表<span style=\"color:red\">雄</span>酮醋酸酯经过氧甲酸环氧化、高碘酸开环、IBX氧化、脱水和碱性水解等5步反应,以55%的总收率合成得到了非雄性激素芳香化酶抑制剂3β-羟基<span style=\"color:red\">雄</span>甾-4-烯-6,17-二酮.在环氧化反应中,利用价廉、易制备的过氧甲酸以几乎定量的收率得到了环氧化合物.使用IBX氧化邻二醇,以98.5%的收率得到氧化产物,避免了使用处理困难并且污染环境的铬试剂.","authors":[{"authorName":"江敏","id":"e478bfe0-208e-4d40-a891-eedb9cf14a31","originalAuthorName":"江敏"},{"authorName":"崔鹏","id":"91ed401e-c66f-41df-ba36-6f08c9699a8d","originalAuthorName":"崔鹏"},{"authorName":"于涛","id":"dffde2e4-50e3-4398-be98-215e1e3e278a","originalAuthorName":"于涛"},{"authorName":"杨帆","id":"e7bdeb82-e4d2-42bc-a46a-8613db59cac6","originalAuthorName":"杨帆"},{"authorName":"汤杰","id":"463f6e76-b476-41cd-bcf8-ec1e609dab13","originalAuthorName":"汤杰"}],"doi":"10.3969/j.issn.1000-0518.2006.12.028","fpage":"1422","id":"bb4b6099-3bef-4f3f-ae66-f1f81d5a1cf8","issue":"12","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"fb0499b0-9a73-4045-887b-8e6206996906","keyword":"3β-羟基<span style=\"color:red\">雄</span>甾烯二酮","originalKeyword":"3β-羟基雄甾烯二酮"},{"id":"736c2718-509a-4751-a5d8-3fd2eff0bb2d","keyword":"IBX","originalKeyword":"IBX"},{"id":"b13d7ec9-7e89-4df5-91fe-02c2a29babe6","keyword":"合成","originalKeyword":"合成"}],"language":"zh","publisherId":"yyhx200612028","title":"3β-羟基<span style=\"color:red\">雄</span>甾-4-烯-6,17-二酮的合成","volume":"23","year":"2006"},{"abstractinfo":"以去氢表<span style=\"color:red\">雄</span>酮(1)为原料,经过氯铬酸吡啶(PCC)氧化得到<span style=\"color:red\">雄</span>甾-4-烯-3,6,17-三酮(2),然后在Co2+存在下用NaBH4还原,得到芳香酶的强效抑制剂3β-羟基<span style=\"color:red\">雄</span>甾-4-烯-6,17-二酮(3). 与文献合成方法相比,反应步骤缩短,反应产率提高. 化合物3的结构经NMR和IR测试技术进行了表征,与文献结果一致.","authors":[{"authorName":"张晓佳","id":"a0e3f7d2-e402-4a37-aba8-0f80dc2d5b48","originalAuthorName":"张晓佳"},{"authorName":"崔建国","id":"768d7ce8-02b0-479c-97c6-e6cc70f98388","originalAuthorName":"崔建国"},{"authorName":"李莹","id":"f3549be9-434c-4b1f-a284-604430db6b60","originalAuthorName":"李莹"},{"authorName":"范建春","id":"1c6c993e-32db-4cd3-ba64-9301f4a7a512","originalAuthorName":"范建春"}],"doi":"10.3724/SP.J.1095.2010.90429","fpage":"615","id":"3e32b24d-4ae2-4cfc-95ac-0496eaea79c5","issue":"5","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"84cb8df9-fa7f-430f-af32-283b5de84ad7","keyword":"去氢表<span style=\"color:red\">雄</span>酮","originalKeyword":"去氢表雄酮"},{"id":"cf0aa859-4ca0-4f2b-a3fe-d0c278518532","keyword":"3β-羟基<span style=\"color:red\">雄</span>甾烯二酮","originalKeyword":"3β-羟基雄甾烯二酮"},{"id":"02f9c6df-2b66-4f6a-a31e-35af35ed0f98","keyword":"合成","originalKeyword":"合成"}],"language":"zh","publisherId":"yyhx201005024","title":"3β-羟基<span style=\"color:red\">雄</span>甾-4-烯-6,17-二酮合成的一种新方法","volume":"27","year":"2010"},{"abstractinfo":"采用对甲苯磺酸(pTsOH)和i氟乙酸(TFA)为催化剂,邻碘酰苯甲酸(IBX)为氧化剂,于40-45℃,在T01.DMSO混合溶剂中,将醋酸去氢表<span style=\"color:red\">雄</span>酮选择性脱氢,简便高效地制备了3β-乙酰氧基.<span style=\"color:red\">雄</span>甾-5.15-二烯-17-酮(I),产率分别为77%和89%.本合成线路有效避免了经溴代脱溴和发酵等合成线路反应繁多、试剂毒性大、成本高以及单纯IBX选择性脱氢反应温度高、反应时间长等不足.然后将化合物I在碱性条件下水解得到3β-羟基.<span style=\"color:red\">雄</span>甾-5,15-二烯-17-酮(Ⅱ),产率92%.最后将化合物Ⅱ与碘化三甲基氧化锍进行迈克尔共轭加成制得目的物15β,16β-亚甲基.<span style=\"color:red\">雄</span>甾-5-烯-3β-醇-17-酮(Ⅲ),产率89%.中间体和目的物经紫外光谱、红外光谱、核磁共振氧谱、质谱及元素分析确证了其化学结构.","authors":[{"authorName":"贺诗华","id":"2b14f0e0-fde8-4e8a-9ec8-d52a03a85213","originalAuthorName":"贺诗华"}],"doi":"10.3969/j.issn.1000-0518.2009.04.008","fpage":"405","id":"2fd086f4-7e54-4847-8967-f93367e2121b","issue":"4","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"77f7c9ee-7c9f-40c7-9f9e-5f80a26dc617","keyword":"醋酸去氢表<span style=\"color:red\">雄</span>酮","originalKeyword":"醋酸去氢表雄酮"},{"id":"ba4fe187-e69d-4cc2-86be-81d24c3bdb7d","keyword":"IBX","originalKeyword":"IBX"},{"id":"d51fa099-b86a-47b6-bbd4-db9f43e7b3ac","keyword":"15β","originalKeyword":"15β"},{"id":"cad463b9-5284-48e8-94a2-5186846f3d94","keyword":"16β-亚甲基-<span style=\"color:red\">雄</span>甾烯-3β-醇酮","originalKeyword":"16β-亚甲基-雄甾烯-3β-醇酮"},{"id":"4e882fea-712c-4dad-930f-fc8ee3da9e4e","keyword":"α","originalKeyword":"α"},{"id":"24e47773-c5a2-48d7-b1cf-9dfb73b19575","keyword":"β-不饱和羰基甾体","originalKeyword":"β-不饱和羰基甾体"},{"id":"d13311f5-a635-4804-a9cd-fb20816d58aa","keyword":"中间体","originalKeyword":"中间体"}],"language":"zh","publisherId":"yyhx200904008","title":"简便高效合成15β,16β-亚甲基-<span style=\"color:red\">雄</span>甾-5-烯-3β-醇-17-酮","volume":"26","year":"2009"},{"abstractinfo":"为了研究<span style=\"color:red\">雄</span>烯二酮（4?androstene?3，17?dione， AED）长期暴露对食蚊鱼（ Gambusia affinis）肝脏7?乙氧基?3?异酚恶唑脱乙基酶（EROD）和谷胱甘肽硫转移酶（GST）的影响，分别利用不同浓度的AED（0．14、1．4、14、140 nmol·L－1和420 nmol·L－1）对食蚊鱼仔鱼进行180 d的水浴暴露，同时设丙酮和空白对照组，分别于第180天取样后测定肝脏的EROD和GST活性．结果表明，与对照组相比，AED对食蚊鱼雌性幼鱼的体重和体长均起到显著的抑制作用，对食蚊鱼雄性幼鱼的体重和体长的影响不明显，只有最高浓度起抑制作用． AED对食蚊鱼幼鱼EROD的抑制作用与暴露浓度呈显著的剂量关系．各浓度组AED对雌性食蚊鱼幼鱼和雄性食蚊鱼幼鱼GST活性的影响大致呈现出倒“U”曲线的趋势．","authors":[{"authorName":"侯丽萍","id":"549aa620-a9ef-490d-9372-a44e300f810c","originalAuthorName":"侯丽萍"},{"authorName":"舒琥","id":"89bf4d65-419b-4ae6-b74a-23b70fc2584c","originalAuthorName":"舒琥"},{"authorName":"李海鹏","id":"f6e0f095-7b8d-4ae9-957e-26754c912720","originalAuthorName":"李海鹏"},{"authorName":"刘珊","id":"4d59d2ff-18e7-46a2-8a33-99d1f8b64b46","originalAuthorName":"刘珊"},{"authorName":"赵建亮","id":"f7778131-ba13-4661-b94c-8a2f03e90bec","originalAuthorName":"赵建亮"},{"authorName":"方展强","id":"63527615-0003-4124-b4dd-c4d57ebcff26","originalAuthorName":"方展强"}],"doi":"10.7524/j.issn.0254-6108.2015.03.2014071001","fpage":"442","id":"4c35572a-73ad-4a4a-b456-82af8d1bf983","issue":"3","journal":{"abbrevTitle":"HJHX","coverImgSrc":"journal/img/cover/HJHX.jpg","id":"43","issnPpub":"0254-6108","publisherId":"HJHX","title":"环境化学   "},"keywords":[{"id":"133d05d5-fea7-4d3e-802f-4f95f2791bfe","keyword":"<span style=\"color:red\">雄</span>烯二酮","originalKeyword":"雄烯二酮"},{"id":"f4a6f146-80a1-454f-9b9b-f70b84a52dc3","keyword":"食蚊鱼","originalKeyword":"食蚊鱼"},{"id":"890e12ac-fd37-46d0-885d-41275f574fd8","keyword":"长期暴露","originalKeyword":"长期暴露"},{"id":"4da0db95-5149-4bf0-be3b-b71dbd7be250","keyword":"生物转化酶","originalKeyword":"生物转化酶"}],"language":"zh","publisherId":"hjhx201503006","title":"<span style=\"color:red\">雄</span>烯二酮长期暴露对食蚊鱼肝脏生物转化酶系的影响?","volume":"","year":"2015"},{"abstractinfo":"建立了建康人头发中内源性类固醇兴奋剂睾酮、表睾酮、<span style=\"color:red\">雄</span>酮、苯胆烷醇酮和脱氢表<span style=\"color:red\">雄</span>酮的气相色谱-串联质谱(GC-MS/MS)分析方法.头发经碱水解后,以乙醚提取,经衍生化后采用GC-MS/MS的多反应监测模式(MRM)分析.方法的线性关系良好,检出限达0.1～0.2 pg/mg;提取回收率为74.6% ～104.5% ;日内测定的准确度为90.1% ～113.7% ,日内及日间测定的精密度均小于17.5% .应用所建立的方法测定了80例中国健康人头发中睾酮、表睾酮、<span style=\"color:red\">雄</span>酮、苯胆烷醇酮和脱氢表<span style=\"color:red\">雄</span>酮的生理水平,为内源性类固醇兴奋剂滥用的判断提供了方法和基础数据.","authors":[{"authorName":"沈敏","id":"92140a83-7a22-492a-8475-d2649e78ed09","originalAuthorName":"沈敏"},{"authorName":"向平","id":"41ade3e9-e85d-41bd-bf7b-568ee4ed1ec1","originalAuthorName":"向平"},{"authorName":"沈保华","id":"4d1df62a-cae0-408a-9531-1336a5f8b6bc","originalAuthorName":"沈保华"},{"authorName":"王萌烨","id":"d2c99118-e749-49db-ba7d-0c4fda0f4052","originalAuthorName":"王萌烨"}],"doi":"","fpage":"454","id":"e168ca47-0e32-4784-b293-91be7ced7246","issue":"4","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"cc06b47f-8fb7-42b6-91bf-750720cf1dcb","keyword":"气相色谱-串联质谱","originalKeyword":"气相色谱-串联质谱"},{"id":"9b1c7a9f-f5ce-4142-833e-b9ae28bc7c56","keyword":"内源性类固醇激素","originalKeyword":"内源性类固醇激素"},{"id":"222b3ce3-d3f2-43fd-81e9-ccbd31d0105f","keyword":"毛发","originalKeyword":"毛发"}],"language":"zh","publisherId":"sp200804011","title":"头发中内源性类固醇激素的气相色谱-串联质谱分析","volume":"26","year":"2008"},{"abstractinfo":"建立了一种用于10种蛋白同化激素的同时分离检测的高效液相色谱法.根据被分析物的性质,以C18反相色谱柱为分离柱,以乙腈和水为流动相,采用梯度洗脱方式,并在194～290 nm的范围内快速调节检测波长,使各物质均在最大吸收波长处被检出.在优化的条件下,10种被测组分在10 min内实现了快速的基线分离,检出限在0.01～0.10 μg/mL范围内.在兔血浆中进行加标回收率测定,10种被测组分的加标回收率为70.3% ～120% .选取美<span style=\"color:red\">雄</span>醇为代表进行实际动物实验,成功检测到耳脉注射美<span style=\"color:red\">雄</span>醇后兔血浆内的美<span style=\"color:red\">雄</span>醇成分.实验结果表明该方法可行,快速简便,准确可靠.","authors":[{"authorName":"张兰","id":"117e2fd6-8797-4425-82f4-3cee336740df","originalAuthorName":"张兰"},{"authorName":"陈金凤","id":"59f976da-b6e1-411e-9461-b56a4c8f86c0","originalAuthorName":"陈金凤"},{"authorName":"童萍","id":"a6e2c666-a6bc-4724-be7c-974d7c3135ab","originalAuthorName":"童萍"},{"authorName":"李天麟","id":"8f8be5aa-bef0-449e-8871-028150a2da4d","originalAuthorName":"李天麟"}],"doi":"","fpage":"449","id":"a6b1eec7-4231-4972-b1b4-83e49c1b28f0","issue":"4","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"10d3dd19-bd6b-4307-aac1-e945756466d5","keyword":"高效液相色谱","originalKeyword":"高效液相色谱"},{"id":"bfd92387-d4fc-49ac-a7e7-f51240e9f3a1","keyword":"蛋白同化激素","originalKeyword":"蛋白同化激素"},{"id":"cea5849d-e76c-4e75-a199-71b4f9c715e4","keyword":"美<span style=\"color:red\">雄</span>醇","originalKeyword":"美雄醇"},{"id":"f294d3ea-5c40-4e30-aa92-aa686b5a70fc","keyword":"兔血浆","originalKeyword":"兔血浆"}],"language":"zh","publisherId":"sp200804010","title":"高效液相色谱法同时测定血浆中的10种蛋白同化激素","volume":"26","year":"2008"},{"abstractinfo":"建立了采用超高效液相色谱-串联质谱(UPLC-MS/MS)同时测定猪、牛、羊和鸡肌肉组织及鸡蛋中睾酮、甲基睾酮、黄体酮、群勃龙、勃地龙、诺龙、美<span style=\"color:red\">雄</span>酮、司坦唑醇、丙酸诺龙、丙酸睾酮及苯丙酸诺龙等11种甾体激素多残留的分析方法.试样在碱性条件下用叔丁基甲醚提取,冷冻离心脱脂净化,以乙腈和甲酸水溶液为流动相,梯度洗脱,反相液相色谱分离.采用电喷雾离子化、多反应监测方式(MRM),对11种甾体激素同时进行定性定量测定.动物肌肉和鲜蛋中睾酮、甲基睾酮、勃地龙、美<span style=\"color:red\">雄</span>酮及司坦唑醇的检出限为0.3 μg/kg,群勃龙、诺龙、黄体酮、丙酸诺龙、丙酸睾酮及苯丙酸诺龙的检出限为0.4 μg/kg.在动物组织及鸡蛋中添加1,2及10 μg/kg 水平的药物回收试验中,睾酮、甲基睾酮、勃地龙、美<span style=\"color:red\">雄</span>酮及司坦唑醇的回收率均在62.3%～105%之间,相对标准偏差为0.5%～15%;群勃龙、诺龙、黄体酮、丙酸诺龙、丙酸睾酮及苯丙酸诺龙的回收率大于50.0%,相对标准偏差小于16%.11种甾体激素在1～100 μg/L范围内,线性关系良好,相关系数都大于0.99.该方法的样品前处理简单、快速,测定灵敏、准确,选择性好,可满足动物源食品中甾体激素类药物多残留的同时测定.","authors":[{"authorName":"贺利民","id":"466538a5-0916-411c-b22c-d7a6a4e336b9","originalAuthorName":"贺利民"},{"authorName":"黄显会","id":"9c2b8bf7-a460-444c-bf67-54bf99f43d07","originalAuthorName":"黄显会"},{"authorName":"方炳虎","id":"9a8ce033-0bb5-4069-9cec-b70e4f7d3be8","originalAuthorName":"方炳虎"},{"authorName":"黄士新","id":"575ffdf3-1f41-4760-be69-b6aea1054ee8","originalAuthorName":"黄士新"},{"authorName":"曹莹","id":"8e9b7d3a-0889-4b6c-8a73-3c41012706a5","originalAuthorName":"曹莹"},{"authorName":"陈建新","id":"01625f3b-98c5-4f75-bafa-5134fd535752","originalAuthorName":"陈建新"},{"authorName":"曾振灵","id":"2309b004-201c-493e-91b2-58dd7b391582","originalAuthorName":"曾振灵"},{"authorName":"陈杖榴","id":"bfa33367-9245-49b2-84b0-7d9ad9ef6dfa","originalAuthorName":"陈杖榴"}],"doi":"10.3321/j.issn:1000-8713.2008.06.013","fpage":"714","id":"4709d1f0-2118-434a-85ca-69fcab8e3b30","issue":"6","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"b4b06057-b496-4ec3-a6a8-59f03f518214","keyword":"超高效液相色谱-串联质谱","originalKeyword":"超高效液相色谱-串联质谱"},{"id":"a1250e7c-f36b-41cb-8d91-73e127afd701","keyword":"甾体激素","originalKeyword":"甾体激素"},{"id":"d6f32875-fc04-4661-b552-bc91025e03b9","keyword":"残留","originalKeyword":"残留"},{"id":"6211c1a5-5087-4451-98fe-b0ec1d129d63","keyword":"动物肌肉组织","originalKeyword":"动物肌肉组织"},{"id":"78231242-f8fc-4c8f-b056-596b57ec37e7","keyword":"鸡蛋","originalKeyword":"鸡蛋"}],"language":"zh","publisherId":"sp200806013","title":"超高效液相色谱-串联质谱法测定动物肌肉组织和鸡蛋中残留的11种甾体激素类药物","volume":"26","year":"2008"}],"totalpage":3,"totalrecord":21}